Barrett食管的临床研究  

Clinical Study of Barrett Esophagus(BE)

作　　者：杨华元[1] 雷健康[2] 张明刚[1] 韩春丽[1] 卢家馨[1] 施光美[1] 

机构地区：[1]中日友好医院,北京100029 [2]汉中市人民医院,陕西汉中723000

出　　处：《现代临床医学》2006年第3期168-170,共3页Journal of Modern Clinical Medicine

摘　　要：目的:分析Barrett食管(BE)的病因、内镜下特征表现及临床病理特点,探讨BE和食管腺癌的关系。方法:分析86例BE患者的临床表现、内镜诊断及病理特点。结果:所有患者均有反流性食管炎的症状。根据症状分为四组:烧心、反酸、吞咽不利、胸骨后或剑突下痛。在内镜下可分为全周型(40例)、岛型(28例)和舌型(18例)。活组织检查结果示:胃底腺型上皮35例、胃贲门交界型上皮39例、特殊型柱状上皮12例。其中不典型增生者15例,尚未发现癌变。结论:BE是反流性食管炎发展的一种结果,其诊断需内镜和活组织检查,对BE的随诊观察可早期发现食管癌。Objective ： To investigate the relationship between BE and esophageal adenocarcinoma by analysis of etiology, endoscopic appearances and morphological characteristics of Barrett esophagus. Methods： Clinical manifestation, endoscopic view and histological findings of 86 patients were reviewed. Results： All patients had symptoms of reflux esophagitis and were grouped into heartburn, acidic reflux, dysphagia and retrostemal （or substernal pain）. Endoscopic view of esophagus covered patterns of circumference （40 cases）, island （28cases）and tongue （18cases）. Histological findings of biopsy showed gastic -fundic -type epithelium （35cases） , junctional - type epithelium （39cases） and specialized columnar epithelium （12cases）. 15 of all patients had atypical proliferation without carcinoma. Conclusion. BE is one major complication of reflux esophagitis and surely diagnosed with endoscope and biopsy. Such patients should be followed up for early diagnosis of esophageal carcinoma.

关 键 词：BARRETT食管 反流性食管炎 病理学 临床 

分 类 号：R571[医药卫生—消化系统]