角膜碱烧伤后免疫复合物检测的实验研究  

An Experimental Study on Immune Complex after Alkali Burns in the Cornea of Rabbits

作　　者：林荣霞[1] 杨德旺[2] 郭峰[2] 

机构地区：[1]南京医科大学第一附属医院眼科,南京210029 [2]上海第二军医大学眼科,上海200433

出　　处：《南京医科大学学报（自然科学版）》1996年第3期256-258,共3页Journal of Nanjing Medical University(Natural Sciences)

基　　金：1991年解放军科技进步三等奖获奖课题项目之一

摘　　要：对兔眼角膜碱烧伤后不同时间的血循环免疫复合物(CIC)的测定,和组织中免疫复合物的检测表明:碱烧伤后14～21天时,CIC 阳性率明显升高(P<0.01),免疫荧光抗体法(IF)和免疫金银染色法(IGSS)可检测到组织中免疫复合物的沉积。提示:碱烧伤后角膜溃疡的形成和加剧与有免疫机理参与造成的损伤有关。The level of circulating immune complex(CIC)and immune complex(IC)in the tissues were determined at different times after alkali burns in the rabbit cornea.The results showed that CIC increased significantly in the 14 to 21 days after alkali burns.While the depo- sition of IC was observed in the burned tissues by means of immunofluorecence(IF)and im- munogold-silver staining(IGSS).It was suggested that immune mechanism did play a timpor- rant role in the pathogenesis of the corneal ulceration after alkali burns.

关 键 词：碱灼伤 免疫复合物 角膜溃疡 烧伤 

分 类 号：R779.13[医药卫生—眼科]