溶血磷脂酸在卵巢癌及某些女性生殖器良性肿瘤患者血浆中的表达  

Expression of Plasma Lysophosphatidic Acid in Patient of Ovarian Cancer and Some Benign Tumours of Woman Genital System

作　　者：佟秀琴[1] 建平[1] 乌云其木格[1] 杨军[1] 刘雪梅[1] 

机构地区：[1]包头市中心医院妇产科,内蒙古包头014040

出　　处：《内蒙古医学杂志》2006年第5期432-434,共3页Inner Mongolia Medical Journal

摘　　要：目的:探讨卵巢癌患者血浆溶血磷脂酸(LPA)水平是否较某些女性生殖器良性肿瘤患者及正常对照者高,评估血浆LPA升高是否可以作为卵巢癌的生物学指标。方法:卵巢癌患者59例,子宫肌瘤患者60例,良性卵巢肿瘤患者60例,分别于术前采取肘静脉血,健康人LPA正常值上限为3.0μmol/L。结果:卵巢癌患者血浆LPA水平明显高于子宫肌瘤及卵巢良性肿瘤患者和健康人血浆LPA水平,P<0.05。而子宫肌瘤及卵巢良性肿瘤患者血浆LPA水平在健康人正常值范围之内。结论:血浆LPA水平可以作为一种卵巢癌的生物学指标。Objective： To investigate the expression of plasma lysophosphatidic acid in patient of ovarian cancer and some benign tumours of woman genital system. Methods： In 59 cases of Carcinoma of the ovary, the plasma concentration of LPA was measured. 60 patients of myoma of uterus and 60 patients of benign tumour of ovary served as control group. The upper limitation in healthy is 3.0μmol/L. Results ： The plasma concentration of LPA was significantly higher in the patients of ovarian cancer than some benign tumours of woman genital system. Conclusion：The plasma lysophosphatidic acid is biology marker of the ovarian cancer.

关 键 词：卵巢癌 生殖器良性肿瘤 血浆溶血磷脂酸(LPA) 

分 类 号：R737.31[医药卫生—肿瘤]