阿司匹林抵抗机制及防治研究进展  

Therapeutic effects of aspirin and mechanisms of aspirin resistance

作　　者：华轶男[1] 谢梅林[1] 

机构地区：[1]苏州大学医学院药理学教研室,江苏苏州215123

出　　处：《中国药理学通报》2006年第6期655-659,共5页Chinese Pharmacological Bulletin

基　　金：江苏省自然科学基金资助项目(NoBK2005029)

摘　　要：阿司匹林是预防心血管事件的常用药物,但并不是所有服用阿司匹林的患者均能获得满意的疗效,这一现象称之为阿司匹林抵抗。对于它的发生机制及防治方法说法众多,该文根据已有文献报道,进行了综述。Aspirin is one of the major drugs used for preventing atherothrombotic vascular diseases, but not effective to all patients or so-called aspirin resistance. However, the mechanisms of this resistance still remains to be elucidated. The recent progresses is reviewed in the therapeatic effect of aspirin and mechanisms of the drug resistance.

关 键 词：阿司匹林 阿司匹林抵抗 血栓 血小板 发生机制 

分 类 号：R-05[医药卫生] R331.124