口腔干燥症患者唾液分泌与相关因素分析  

Correlation between Clinical Manifestation and Salivary Secretion of Xerostomia Patients

作　　者：柏景坪[1] 林梅[1] 

机构地区：[1]四川大学华西口腔医院黏膜病科,四川成都610041

出　　处：《华西口腔医学杂志》2006年第3期240-242,260,共4页West China Journal of Stomatology

基　　金：国家"十五"科技攻关资助项目(2004BA720A28)

摘　　要：目的观察口腔干燥症患者的临床表现及唾液分泌情况,了解唾液分泌减少与临床表征之间的相关关系。方法收集80例口腔干燥症患者的临床资料,并对各项指标进行量化分级,测量5min静息唾液与刺激唾液流率,并进行相关分析。结果80例患者中静息唾液流率下降者占75%,为口腔干燥症主要表现。静息唾液流率与口腔功能的影响程度成负相关,与患者年龄、性别、伴随症状之间无明显相关关系。结论口腔干燥症以静息唾液分泌减少为主要表现;唾液分泌减少不是增龄性变化,且与伴随症状的出现无关。Objective To observe the general status, subjective syndromes, objective signs and salivary secretion of xerostomia patients for studying their correlations. Methods Eighty patients＇ clinical data were collected and classified according to certain standards. The salivary secretion including the unstimulated whole saliva （UWS） and stimulated whole saliva （SWS） in five minutes was measured by spit method. Results Decreased UWS was the main presentation of xerostomia which accouted for seventy five percents. Significantly statistical correlation were found between the decreased UWS and the dry mouth signs but not the age, sex and the accompany syndromes. Conclusion Xerostomia has a high prevalence in middle-aged women with a long course and obvious regularity. The decreased UWS is the main presentation which was not caused by physiological changes of salivary glands and has no correlation with many clinical manifestations.

关 键 词：口腔干燥症 静息唾液 临床表现 

分 类 号：R781.59[医药卫生—口腔医学]