缺氧缺血性脑病新生儿听力筛查  

Screening and analysis of the hearing of hypoxic-ischemic encephalopathy newborns

作　　者：程雁[1] 王俐俐[1] 宣桂华[1] 张晓敏[2] 

机构地区：[1]安徽医科大学第一附属医院儿科,合肥230022 [2]安徽医科大学第一附属医院电测听室,合肥230022

出　　处：《安徽医科大学学报》2006年第3期319-320,共2页Acta Universitatis Medicinalis Anhui

摘　　要：目的探讨新生儿缺氧缺血性脑病(HIE)对听力的影响及可能导致听力障碍的高危因素。方法应用丹麦耳声发射仪(TEOAE)对HIE患儿和正常儿出生后42d内进行听力筛查。结果HIE患儿TEOAE通过率61·5%,与对照组差异有显著性(P<0·05),且多因素Logistic回归分析提示,早产、HIE临床分度、高胆红素血症是其高危因素。结论新生儿HIE能引起新生儿听力障碍,早产、HIE临床分度、高胆红素血症可能是影响HIE新生儿TEOAE不通过的高危因素。Objective To study the influence of neonatal hypoxic-ischemic encephalopathy（HIE） on the hearing ability of newborns and explore related pathogenic factors. Methods Hearing Screening with transient evoked otoacoustic emission （TEOAE） was conducted among 70 HIE neonates and 50 normal neonates within 42 days after birth. Results The passing rates of TEOAE between HIE neonates and normal neonates was significantly different. Multivariate Logistic regression analysis revealed that prematures, clinical grades of HIE and hyperbilirabinehia were risk factors. Conclusion HIE causes neonatal hearing impairment. Prematures, clinical grades, and hyperbilirubinemia are risk factors for failing to pass TEOAE.

关 键 词：婴儿 新生 疾病 缺氧缺血 脑/病理生理学 听力检查 

分 类 号：R743.023[医药卫生—神经病学与精神病学] R764.04[医药卫生—临床医学]