528例食管癌放射治疗疗效分析  

Analysis of Radiotherapeutic Efficacy for 528 Patients with Esophageal Carcinoma

作　　者：蔡平[1] 刘庆深[1] 李惜辉[1] 

机构地区：[1]广东省汕头市中心医院放疗科,广东汕头515031

出　　处：《海南医学》2006年第7期4-5,共2页Hainan Medical Journal

摘　　要：目的总结分析食管癌单纯外照射的疗效。方法528例食管癌均行60Co外照射,通过临床各因素与生存率的关系做综合分析。结果全组随访5年以上,1、3、5年生存率分别为59.8%、19.9%、9.7%。食管癌单纯外照射,病变越短,病变部位越高、生存率越高,且放疗剂量以60～70GY/6～7W最佳,放疗剂量高于70GY者,5年生存率仅4%(0.01<P<0.05)。结论食管病变长度、病变部位、疗终X线表现、放疗剂量是影响预后的主要因素。本组在死因明确的病例264例中局部复发占67.4%,放射治疗失败的主要原因是局部未控与复发,因此,控制原发灶仍是食管癌放射治疗主要关键。Objective To analyze the factor affecting the results and the prognoses of radiotherapy for esophageal carcinoma. Methods 528 patients with esophageal cancer were treated by radiotherapy. All patients used Co60 radiotherapy.To investigate into the relationship between the survival rate and the relevant clinical factors. Results All cases were followed up for 5 years of clinical, The 1-,3- and 5-year survivals were59.8%, 19.9%and 9.7% respectively. The length of tumor is more short, the position of tumor is more high, the survival rate is more high. It is better for patient with esophageal carcinoma to be irradiated between 60- 70Gy/6-7wk; Those treated with tumor dose more than 70Gy gave 5 year survivals of 4%（0.01〈P〈0.05）. Conclusions The length of tumor, the position of tumor, X-ray manifestation after radiotherapy and dose of irradiation are the main prognostic factors. The causes of death of the 264 cases were chiefly due to in effective control and recurrence of local lesion （67.4 %）. The reason for failure of radiotherapy was chiefly due to in effective control and recurrence of local lesion. Therefore, the key to the radiotherapy of csophaggeal carcinoma is to control the protopathic focus effectively.

关 键 词：食管癌 单纯外照射 生存率 

分 类 号：R735.1[医药卫生—肿瘤]