大面积脑梗死并发低钠血症临床观察  

Clinical observation of massive cerebral infarction accompanied by hyponatremia.

作　　者：李富康[1] 钟春梅[2] 马可夫[1] 付学军[1] 褚晓凡[1] 

机构地区：[1]暨南大学医学院第二临床医院神经内科,广东省深圳市518020 [2]深圳市儿童医院

出　　处：《中国综合临床》2006年第7期609-610,共2页Clinical Medicine of China

摘　　要：目的探讨大面积脑梗死急性期并发低钠血症对预后的影响。方法收集首次发病的急性大面积脑梗死患者81例,测定其血清钠浓度,对发生低钠血症患者的预后进行分析。结果大面积脑梗死后低钠血症发生率为29.6%,并发低钠血症患者的病死率高于血钠正常者(P<0.05);低钠血症患者发生出血性脑梗死、脑水肿亦较血钠正常者多(P<0.05)。结论大面积脑梗死后低钠血症发生率较高,是预后差的因素之一,且与出血性脑梗死、脑水肿关系密切。Objective To explore the effect of hyponatremia on prognosis of acute massive cerebral infarction. Methods Serum sodium levels were measured in 81 patients with initial massive cerebral infarction. The prognosis of the patients with hyponatremia was analyzed. Results The incidence rate of hyponatremia after massive cerebral infarction was 29.6%. The mortality in the patients with hyponatremia was significantly higher than those in patients without hyponatremia （ P 〈 0.05 ）. The prevalence rate of hyponatremia accompanied by hemorrhagic infarction and brain edema were also significantly higher than those in patients without hyponatremia （ P 〈 0.05 ）. Conclusion The incidence of hyponatremia after massive cerebral infarction is high, which is one of the factors of poor outcome, and closely associated with hemorrhagic infarction and brain edema.

关 键 词：脑梗死 低钠血症 脑水肿 

分 类 号：R743.3[医药卫生—神经病学与精神病学]