31例抑郁症患者探究性眼球轨迹运动分析  

Explorative Eye Tracking Movement of Patients with Depression

作　　者：潘超[1] 单敏 朱日升[1] 韩永华[1] 

机构地区：[1]北京大学精神卫生研究所,北京100083 [2]新疆阜康准东职工医院,831511

出　　处：《中国心理卫生杂志》2006年第6期407-409,共3页Chinese Mental Health Journal

摘　　要：目的探讨抑郁症患者探究性眼球轨迹标记运动的临床特征。方法应用探究性眼球轨迹运动标记记录仪(Type-Ⅳ)和汉密尔顿抑郁量表(HamiltonDepressionScale,HAMD)对31例抑郁症患者于治疗前后分别进行两次检查,间隔时间(34±8)天;31例正常人对照组只作一次检查。结果判别分析值(Discriminantanalysis,D分值)在抑郁症组前后两次检查的结果(0.52±1.58,0.79±1.44)均高于正常人对照组(-1.00±0.85),差异均有统计学显著性(t=4.40、5.80,P<0.01)。抑郁症组前后两次检查HAMD量表评分差异有显著性(32.14±5.72,17.48±7.82,t=11.91,P<0.01),但前后两次探究性眼球轨迹运动主要指标之间比较其差别无显著性(P>0.05)。结论抑郁症组与正常对照组探究性眼球轨迹运动结果不同,抑郁症组经过抗抑郁剂治疗后,探究性眼球轨迹运动主要指标前后两次比较无明显变化。Objective： To explore eye tracking movements of patients with depression. Methods： Thirty-one patients with depression were tested by tracking of exploratory eye movement （ Type-Ⅳ ） before and after treatment （ mean interval 34±8 days）, at the same time HAMD was applied. Thirty-one normal controls were tested by tracking of exploratory eye movement either. Results： There were significant differences of discriminant analysis between the results of patients and controls （0.52±1.58, 0.79±1.44, vs. -1.00±0.85, t=4.40,5.80, P〈0.01）; HAMD score decreased significantly after treatment （32. 14±5.72, 17.48±7. 82, t=11.91, P 〈 0. 01 ）, but no significant differences were noted in main indexes of eye tracking movements （ P 〉 0. 05 ） ; Conclusion： There is statistical difference in exploratory eye tracking movements of depressive patients and that of controls. After depression improved, no significant changes were noted between the main indexes of eye tracking movements of the first test and that of the second test.

关 键 词：抑郁症 病例对照研究 探究性眼球轨迹运动 

分 类 号：R749.4[医药卫生—神经病学与精神病学]