Hilar Cholangiocarcinoma with Synchronous Metastases to Breast and Skeletal Muscle: A Case Report and Literature Review  

肝门部胆管癌伴乳腺和骨骼肌同时转移1例报告及文献综述(英文)

作　　者：丁光辉[1] 杨家和[1] 程树群[1] 龚华[1] 刘凯[1] 戴炳华[1] 龚彪[1] 赵丽华[1] 丛文铭[1] 吴孟超[1] 

机构地区：[1]上海第二军医大学东方肝胆外科医院,200438

出　　处：《The Chinese-German Journal of Clinical Oncology》2006年第3期216-218,共3页中德临床肿瘤学杂志（英文版）

摘　　要：Hilar cholangiocarcinoma has been reputed as a slow growth tumor in the past. Skeletal muscle is one of the most unusual sites of metastasis from any malignancy. We report herein a case of hilar cholangiocarcinoma with synchronous metastases to skeletal muscle and breast, and review the literature. The patient was a 48-year-old woman who presented with jaundice and weight loss. An inoperable hilar cholangiocarcinoma was diagnosed. She was treated with a combination of endoscopic plastic stent biloiary drainage and three-dimensional conformal radiotherapy （3DCRT）. Good response was achieved. Ten months later, she exhibited with a painful metastatic mass in the muscle rectus femoris of left thigh and a painless mass in the left breast. She underwent operation to relieve the pain, but died from liver failure after 8 months. The literature only offers isolated cases of cholangiocarcinoma with distant metastases, of which the common sites were cervical lymph node, bone, and portal venous system. Most patients were presented with multiple metastases with extensive local disease.

关 键 词：hilar cholangiocarcinoma distant metastasis endoscopic stent three-dimensional conformal radiotherapy palliative treatment 

分 类 号：R735.8[医药卫生—肿瘤]