常规放疗与低分割放疗治疗骨转移癌疼痛的临床观察  

Observation on Effect of Conventional Fraction and hypo Fraction Radiotherapy in Treating bone Metastases Patients

作　　者：胡家柱[1] 谢方云[2] 曹小龙[1] 黎益华[1] 毛志达[2] 

机构地区：[1]广州市番禺区人民医院肿瘤科,广东广州511400 [2]中山大学肿瘤防治中心放疗科,广东广州510060

出　　处：《国际医药卫生导报》2006年第10期19-20,共2页International Medicine and Health Guidance News

摘　　要：目的观察常规放疗与低分割放疗治疗骨转移癌疼痛的临床疗效。方法90例患者分2组,常规放疗组45例:采用常规分割照射,DT200cGy/次,每周5次,DT3000～5000cGy;低分割放疗45例:采用低分割照射,300～500cGy/次,每周3～5次,DT2000～3600cGy。结果放疗起到了明显的止痛作用,常规分割放疗组与低分割放疗组止痛效果大致相似,差异无显著性(P>0.05)。结论骨转移癌的放射治疗应根据病情来决定:对一般情况好,预计生存期长的患者应积极给予全剂量的分割治疗,而对于病情相对较重、行动不方便、预计生存期短的患者,应采取低分割照射,同样可以起到止痛作用。Objective To observation the pain relief efficacy with conventional fraction and hypo fraction radiotherapy for bone metastases. Methods Of 90 patients with bone metastases , 45 cases received conventional fraction ： D r200cGy/f, 5 fractions per week D r3000～5000cGy. 45 cases received hypo fraction ： DT300～ 500cGy/f, 3～5 fraction per week, DT2000-3600cGys. Results Radiotherapy can produce a higher pain relief rate of bone metastases . Compared conventional fraction with hypo fraction, no significant difference was found （P〉 0. 05）.Conclusion Radiotherapy of bone metastases should be determined by the patient condition. For the patients with long life span should be treated actively by conventional fraction and high doses . The patients with severe disability and pain should be treated with hypo fraction.

关 键 词：骨转移癌 放射治疗 疼痛 

分 类 号：R738.1[医药卫生—肿瘤]