角膜碱烧伤房水一氧化氮及一氧化氮合酶变化  

Dynamic change of nitric oxide in aqueous humor after corneal ocular alkli burn of rabbits.

作　　者：刘森玉[1] 崔巍[1] 

机构地区：[1]内蒙古自治区医院眼科,内蒙古呼和浩特010017

出　　处：《眼外伤职业眼病杂志》2006年第6期404-406,共3页Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries

摘　　要：目的探讨角膜碱烧伤后房水一氧化氮(NO)与炎症反应的关系。方法用健康家兔动态观察对照组、实验组和对侧眼组眼内炎症反应及房水一氧化氮合酶(NOS)和NO2-/NO3-的活性。结果角膜碱烧伤后炎症反应与房水NOS和NO活性呈动态变化,实验组明显高于对侧眼组,且两组均高于对照组。结论房水NO的变化与角膜碱烧伤后的眼内炎症反应密切相关。Objective To investigate the dynamic change of nitric oxide（NO） in aqueous humor after corneal alkli bum of rabbits. Methotis The activities of NOS and NO2^-/NO3^- and ocular inflammation were observed in control group, experimental group and opposite eye group. Results The activities of NOS and NO2^-/NO3^- and ocular inflammation were changed dynamically .The activities of NOS and NO2^-/NO3^- of experimental group were higher than that of opposite eye group, and the activities of NOS and NO2^-/NO3^- of above both groups were higher than that of control group. Conclusion NO is related close to ocular inflammatory reaction after corneal alkli burn.

关 键 词：碱烧伤 炎症 一氧化氮 

分 类 号：R779.13[医药卫生—眼科]