TACE联合PAI治疗原发性肝癌疗效分析  

Clinic Study on the Curative Effect of Sequential Therapy with TACE and PAI for Hepatocellular Carcinoma

作　　者：杨海山[1] 王宁[2] 商健彪[2] 安东洪 

机构地区：[1]吉林大学中日联谊医院放射科,长春130031 [2]沈阳军区总医院放疗科,110015

出　　处：《临床放射学杂志》2006年第6期554-557,共4页Journal of Clinical Radiology

基　　金：吉林省重点科技项目(编号:吉发改高技联字[2004]987号)

摘　　要：目的研究经导管动脉化学栓塞(TACE)联合经皮乙酸注射(PAI)治疗原发性肝癌的疗效。资料与方法选择52例肝癌患者,分为TACE联合PAI治疗组和单纯TACE治疗组,比较两组治疗效果。结果联合组与单纯TACE组有效率分别为61.5%、30.8%,两组间差异有统计学意义(P<0.05),1、2年生存率分别为80.8%,61.5%;69.2%,30.8%,差异有统计学意义(P<0.01)。结论与单纯TACE相比,TACE联合PAI治疗中、晚期巨块型肝癌有较好的临床疗效。Objective To study the curative effect of sequential therapy with TACE and PM for hepatoceilular carcinoma. Materials and Methods A total of 52 patients with HCC were enrolled. 26 patients were treated with TACE PAl and other 26 patients were treated with TACE alone, the effect of two groups was compared. Results Objective responses （CR ＋ PR） were achieved in 16 of 26 （61.5 % ） patients in the TACE PAI group compared with 8 of 26 （30.8 % ） in the TACE group （P 〈 0.05）. The 1, 2 year survival rate of TACE PAl group and TACE alone group was 80.8%, 61.5% ; 69.2%, 30.8% respectively （ P 〈 0.01 ）. Conclusion Sequential therapy with TACE and PM is superior to TACE alone for patients with large HCC.

关 键 词：肝细胞性肝癌 乙酸 化学栓塞 

分 类 号：R735.7[医药卫生—肿瘤] R735[医药卫生—临床医学]