脑电图标准化闪光刺激试验在癫诊断中的意义  

Significance of Standardized Photic Stimulation in Diagnosis of Children with Epilepsy

作　　者：蔡翔[1] 秦炯[1] 刘晓燕[1] 杨志仙[1] 张意萍[1] 冯保蓉[1] 

机构地区：[1]北京大学第一医院儿科,北京100034

出　　处：《实用儿科临床杂志》2006年第11期696-698,共3页Journal of Applied Clinical Pediatrics

基　　金：卫生部临床学科重点项目基金资助(20010912)

摘　　要：目的 研究儿童癫痫 与光敏感性的关系。方法 筛选具有光敏感性癫痫发作相关症状患者进行录像脑电监测，并予标准化闪光刺激（IPS），观察癫痫患者的临床特点及其光敏感性。结果 共收集癫痫患者67例。男41例，女26例；年龄1～16岁，其中28例符合癫痫综合征。7例IPS试验阳性，其中5例符合癫痫综合征：少年失神3例、少年肌阵挛1例、Dravet综合征1例。治疗6例，丙戊酸钠治疗5例中4例发作明显好转，托吡酯治疗1例效果不明显，但指导其避免不良光诱发因素后发作亦有改善。结论 标准化的IPS试验有助于检出癫痫患者的光敏感性，指导全面治疗。Objective To investigate the photosensitivity among pediatric epileptic patient,and their characters. Methods From Jun 2005 to Dec 2005,intermittent photic stimulation（IPS） and EEG were performed toward children who came with clinical epileptic seizures and symptoms found in photosensitive epilepsy. Children with epilepsy their clinical information and their IPS results were further analyzed. Results Sixty- seven epileptic patients were found during that period, 41 males, 26 females, aged from one to sixteen years old. Among the 67 epileptic patients,28 of them suited for epileptic syndromes. Seven were found photosensitive positive, and 5 of them suited for various epileptic syndrome：juvenile absence 3, juvenile myoclonic epilepsy 1, Dravet syndrome 1. Six of them accepted treatment. Anwng the 5 patients received valporate, 4 of them showed clinical improvement; another one received topiramate, cli-nically did not improve until avoiding provocative visual stimulation in daily life. Conclusions Standardized intermittent photic stimulation would help to screen photosensitivity among epileptic patients, and further to provide a more complete treatment.

关 键 词：癫痫 光敏感性 标准化闪光刺激 儿童 

分 类 号：R742.1[医药卫生—神经病学与精神病学]