钯－膦－酸体系催化叔丁醇羰化制备异戊酸酯  

CARBONYLATION OF t BUTYL ALCOHOL TO ESTER OF i VALERIC ACID CATALYZED BY PALLADIUM CATALYST

作　　者：周宏英[1] 吕士杰[1] 陈静[1] 李红兵[1] 傅宏祥[1] 汪汉卿[1] 

机构地区：[1]中国科学院兰州化学物理研究所

出　　处：《催化学报》1996年第4期311-314,共4页

基　　金：国家自然科学基金及石油化工科学研究院基金

摘　　要：研究了Ｐｄ（ＯＡｃ）２－ＰＰｈ３－ｐ－Ｔｓ催化剂体系存在下，叔丁醇羰化生成异戊酸酯的反应．典型的反应条件是：温度１２０～１６０℃，压力３．０～７．０ＭＰａ，Ｐｄ浓度３．６ｍｍｏｌ／Ｌ，ｎＰｄ∶ｎＰＰｈ３∶ｎｐ－Ｔｓ＝１∶３０∶８０，时间１２～２４ｈ．在上述反应条件下，叔丁醇羰化生成异戊酸酯的产率为１１．０％～８３．６％，选择性为１３．１％～９５．０％．t Butyl alcohol was carbonylated into ester of i valeric acid in the presence of a palladium acetate triphenylphosphine p toluenesulfonic acid (Pd(OAc) 2 PPh 3 p Ts) catalytic system without any halogen promoter or other extreme conditions. Typical reaction conditions were: θ =120￣160℃; p CO =4 0￣7 0 MPa; n Me 3COH ∶ n ROH ∶ n Pd =490∶40000∶1; c Pd =3 6 mmol/L; n Pd ∶ n PPh 3 ∶ n p Ts =1∶30∶80; solvent=methanol, ethanol, i propanol or n butanol ; t =12￣24 h. Under these experimental conditions, high yield (83 6%) and selectivity (95 0%) for ester of i valeric acid were obtained. It was also found that the catalytic activity was strongly influenced by the nature of the solvent.

关 键 词：叔丁醇 羰化反应 异戊酸酯 钯催化剂 三苯基膦 

分 类 号：TQ225.25[化学工程—有机化工] O614.823[理学—无机化学]