免疫金银标记术对口腔粘膜病鉴别诊断的意义  

Differential diagnosis of oral mucosal diseases using immunogold silver staining technology

作　　者：张水龙[1] 曹宏康[1] 

机构地区：[1]上海第二医科大学口腔医学院口腔内科

出　　处：《实用口腔医学杂志》1996年第3期169-171,共3页Journal of Practical Stomatology

摘　　要：用免疫金银染色（ＩＧＳＳ）技术对６５例临床较常见但易混淆的４种口腔粘膜病患者的组织标本进行了检测分析。根据扁平苔藓（ＬＰ）和盘状红斑狼疮（ＤＬＥ）的辅助诊断标准和本实验的检测结果表明，在组织病理检查诊断为“慢性粘膜炎”而临床则诊断为ＬＰ（２０例）和ＤＬＥ（１５例）的病例中，有１９例和１４例被分别确诊为ＬＰ和ＤＬＥ；化１０例临床和病理均不能确诊的慢性粘膜炎中，７例确诊为ＬＰ，５例确诊为ＤＬＥ；在１０例口腔白斑（ＬＫ）中１例确诊为ＬＰ；而１０例口腔良性过角化（ＨＫ）全部为阴性反应。Lichen planus(LP),discoid lupus erythematosus(DLE),leukoplakia(LK) and hyperkeratosis(HK) are common in clinic and often confused with each other and difficult to be distinguished in some cases. 65 cases with these diseases were surveyed and diagnosed with immnogold silver staining(IGSS) technique. The diagnosis by IGSS were compared with those according to the routine clinic histopathology(RCH).Nineteen LP and 14 DLE in RCH diagnosed cases of 20 LP and 15 DLE were confirmed with IGSS,1 of 10 LK was proven to be LP,respectively. The total of 10 HK presented negative reactions and the diagnosis with IGSS was in accordance with that of histopathological examination.

关 键 词：免疫金银染色 扁平苔 口腔粘膜疾病 

分 类 号：R781.504[医药卫生—口腔医学]