丙泊酚静脉维持麻醉用于婴幼儿唇裂手术的临床应用  

Propofol Intravenous Anesthesia for Cleft Lip Operations in Infants

作　　者：李秀兰[1] 秦秦[2] 龙卫红[2] 

机构地区：[1]西北工业大学医院麻醉科,陕西西安710072 [2]陕西省人民医院麻醉科,陕西西安710068

出　　处：《口腔颌面外科杂志》2006年第2期121-122,144,共3页Journal of Oral and Maxillofacial Surgery

摘　　要：目的:婴幼儿唇裂手术中,应用丙泊酚与传统的氯胺酮静脉麻醉方法比较。方法:Ⅰ～Ⅱ度唇裂手术婴幼儿55例,男34例,女21例;平均体重(8.3±2.5)kg。全部患儿均采用气管插管全麻。将患儿随机分为两组,Ⅰ组(氯胺酮组n=29),Ⅱ组(丙泊酚组n=26)。结果:Ⅰ组拔管时间、清醒时间明显较Ⅱ组长(P<0.05),且躁动哭闹人数、术后恶心呕吐发生率明显高于Ⅱ组(P<0.05)。结论:丙泊酚用于婴幼儿唇裂修复术,具有苏醒快、气道分泌物少、术后恢复安全系数高的特点。而氯胺酮+γ-羟基丁酸钠麻醉,具有诱导插管平稳,但术后苏醒延迟、恶心呕吐、躁动哭闹发生率较高等特点,尤应注意术后呼吸道的管理。Objective： To compare the advantages and disadvantages of propofol and ketamine in intravenous anesthesia for cleft lip operation in infants. Methods： 55 cases of stage 1-2 deft lip infants randomly divided into 2 groups, group Ⅰ （ketamine, n=29）, group Ⅱ （propofol, n=26）. General anesthesia with the techniques of tracheal intubation were used in all cases. Results： Extubation time and recovery time of group Ⅰ was obviously longer than group Ⅱ （P〈0.05）; cases of restlessness, crying, postoperative nausia and vomiting of group Ⅰ were significantly higher than group Ⅱ （P〈0.05）. Conclusion： Propofol intravenous anesthesia in infantile cleft lip operation provides quicker recovery, fewer airway secretions, and higher safety efficiency for postoperative recovery. Ketamine leads to stable intubation, but high incidence of awake delay, vomiting restlessness, and crying. More attention to be paid on respiratory tract management postoperatively.

关 键 词：丙泊酚 氯胺酮 麻醉 婴幼儿 唇裂 

分 类 号：R782.054[医药卫生—口腔医学]