多发性硬化20例临床特点分析  

Clinical analysis on multiple sclerosis.

作　　者：袁波[1] 邹文[1] 童晓欣[1] 张海鸥[1] 王诚[1] 

机构地区：[1]北京大学深圳医院,深圳518036

出　　处：《华中医学杂志》2006年第3期197-198,共2页Central China Medical Journal

摘　　要：目的探讨多发性硬化(MS)的临床特点。方法回顾分析20例MS患者的临床资料。结果MS多见于青年女性,病程多出现缓解与复发,上呼吸道感染、劳累可为其诱因,磁共振成像、诱发电位检查、脑脊液常规有助诊断,视神经、脊髓受累多见,脑脊液显示免疫活性增高,糖皮质激素+免疫抑制剂治疗有效。结论根据临床特点、结合MRI、神经电生理及脑脊液免疫学能明显提高临床确诊率。Objective To study the clinical features of multiple sclerosis （MS）. Methods The clinic features and outcomes were analyzed in 20 patients with MS. Results MS mainly affects young and middle-aged women. Alleviation and recurrence of the disease happen alternately during the course. Upper respiratory tract infection and tiredness are the main inducements. MRI, electrophysiology and immunology are helpful for diagnosis. Optic nerves and spinal cord are often involved. The immunoeompetence of cerebrospinal fluid （CSF） is increased. Glucocorticoid plus immunosuppressant therapy is effective. Condusion In addition to clinical features, MRI, neuro-electrophysiology and CSF immunology are greatly helpful for definite diagnosis.

关 键 词：多发性硬化 磁共振成像 诱发电位 

分 类 号：R744.51[医药卫生—神经病学与精神病学]