小剂量黛力新联合匹维溴胺治疗肠易激综合征  

Low dose deanxit combining pinaverium bromide for irritable bowel syndrome

作　　者：黄海滨[1] 方苗[1] 陈维婵[1] 郑晓菲[1] 

机构地区：[1]广东省汕头市中心医院,汕头515031

出　　处：《中原医刊》2006年第13期16-17,共2页Central Plains Medical Journal

摘　　要：目的探讨小剂量抗焦虑—抑郁药黛力新联合匹维溴胺对肠易激综合征的治疗效果。方法将68例肠易激综合征(IBS)患者随机分成实验组35例和对照组33例,实验组给予黛力新片1片/d,早晨口服,匹维溴胺片50mg,3次/d;对照组给予硝苯地平片10 mg,3次/d,谷维素片20mg,3次/d,两组疗程均为8周,治疗期间均停用其他药物。观察比较两组疗效。结果实验组治疗8周的总有效率91.4%,疗效明显高于对照组的48.5%,差异有统计学意义(P<0.01)。结论小剂量黛力新联合匹维溴胺治疗肠易激综合征具有良好的效果。Objective To explore the therapeutic effect of low dose deanxit （ antianxiety - depression drug ） combining pinaverium bromide for irritable bowel syndrome （IBS）. Methods Sixty - eight cases of IBS were randomly divided into experimental group and control group, the patients in experimental group took deanxit one time daily in early morning and pinaverium bromide 50 mg three times daily orally , the patients in control group took nifedipine 10mg three times daily and oryzanolum 20mg three times daily orally, the courses of treatment were 8 weeks, the other kinds of drug were stopped in the treatment period, to observe and compare the therapeutie effect between the two groups. Results The overall effective rate in experimental group was 91.4% （in eighth week ）, the clinical therapeutic effect was significantly higher than the control group （48.5% in eighth week）, P 〈 0. 01. Conclusion Low dose deanxit （antianxiety - depression drug） combining pinaverium bromide has good therapeutic effect on IBS.

关 键 词：黛力新 匹维溴胺 肠易激综合征 硝苯地平 谷维素 

分 类 号：R574.4[医药卫生—消化系统]