赛庚啶联合双歧三联活菌胶囊治疗腹泻型肠易激综合征疗效观察  

The Efficvacy Abservation of Treating Diarrhea-type Irritable Bowel Syndrome(IBS) with Cyproheptadine and Bifidobacterium Bifidumsine Capsules

作　　者：吴晓锐[1] 张锋[1] 詹志刚[1] 郑林[1] 

机构地区：[1]解放军第92医院消化科,福建南平353000

出　　处：《临床军医杂志》2006年第3期284-285,共2页Clinical Journal of Medical Officers

摘　　要：目的探讨赛庚啶联合双歧三联活菌胶囊治疗腹泻型肠易激综合征的疗效.方法 76例腹泻型肠易激综合征病人分为3组,A组26例,给予双歧三联活菌胶囊420 mg,3次/d 口服.B组24例,给予赛庚啶片2～4 mg,2次/d 口服.C组26例,给予赛庚啶2～4 mg,2次/d 口服,加服双歧三联活菌胶囊420 mg, 3次/d 口服.3组的疗程均为4周.结果 A,B,C三组的总有效率分别为61.5%,83.8%,92.3%.C组与A组比较差异有非常显著意义（P〈0.01）,C组与B组无显著差异（P〉0.05）,B组和A组间的差别有显著意义（P〈0.01）.结论赛庚啶联合双歧三联活菌胶囊可以有效地治疗腹泻型肠易激综合征.Objective To study the efficacy of treating diarrhea-type irritable bowel syndrome with cyproheptadine and bitidobacterium bifidum-sine capsules. Methods 76 patients with diarrhea-type irritable bowel syndrome were divided into three groups. The group A that had 26 cases was treated with bifidobactefium bitidum-sine capsules. The group B that had 24 cases was treated with cyproheptadine. The group C that had 26 cases was treated with cyproheptadine and bifidobactefium bifidum-sine capsules. The period of treatment of three groups were all four weeks. To observe the clinic efficacy and the side-effect of the three groups. Results The efficiency ratio of the group A was 61.5% ;The efficiency ratio of the group B was 83.8% ;The efficiency ratio of the group C was 92.3%. The differency of comparation with the group C and the group A was very distinct;The differency of comparation with the group C and the group B wasni distinct;The differency of comparation with the group B and the group A was distinct. Conclusion Diarrhea-type irritable bowel syndrome can be treated with cyproheptadine and bifidobacterium bifidum-sine capsules efficiently.

关 键 词：肠易激综合征 赛庚啶 双歧三联活菌胶囊 

分 类 号：R574.4[医药卫生—消化系统]