羊膜移植及丝裂霉素C联合可拆除缝线小梁切除术治疗难治性青光眼  

Removable Suture Trabeculectomy with Amniotic Membrane Implantation and Mitomycin C for Treatment of Refractory Glaucoma

作　　者：黄芳[1] 付书华[1] 汪昌运[1] 兰绪达[1] 

机构地区：[1]南昌大学第二附属医院眼科,江西南昌330006

出　　处：《江西医学院学报》2006年第3期67-68,72,共3页Acta Academiae Medicinae Jiangxi

摘　　要：目的探讨羊膜移植及丝裂霉素C（MMC）联合可拆除缝线小梁切除术治疗难治性青光眼的效果。方法8例（10眼）难治性青光眼均采用瑞济冷冻干燥羊膜移植联合可拆除缝线小梁切除术，术中于巩膜瓣和结膜瓣下放置0．3mg／mLMMC2min.术后1周、1月及1年，检查记录术眼眼压、滤过泡、前房深度情况。结果术后1周无浅前房出现，术后早期持续性低眼压1例，术后1年除1眼眼压23．78mmHg需用药物控制外，其余9眼眼压在7～18mmHg之间，均保持功能性滤过泡及良好的前房深度。结论羊膜移植及MMC联合可拆除缝线小梁切除术可减少滤过道疤痕的形成，有效控制术后滤过水平，减少术后并发症发生。Objective To explore the efficacy of removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for treatment of refractory glaucoma. Methods Eight patients（10 eyes）with refractory glaucoma underwent removable suture trabeculectomy with amniotic membrane implantation. Trabeculectomy was performed with a limbal-based conjunctival flap using 0.3 mg/mL MMC for 2 rain. The IOP, the filtering bleb and the anterior chamber depth were examined at 1 week, 1 month and 1 year after surgery respectively. Results There was no shallow anterior chamber happened at week after surgery; One eye showed a postoperative hypotony;The lOP was 23.88 mmHg in 1 eye,7-18 mmHg in 9 eyes. There were 10 eyes that maintained functioning blebs and anterior chamber depth during 1 year follow up period. Conclusion Removable suture trabeculectomy with amniotic membrane implantation and mitomycin C for refractory glaucoma can effectively inhibit the scar formation and reduce the incidence of the complications.

关 键 词：羊膜移植 丝裂霉素C 小梁切除术 难治性青光眼 

分 类 号：R775[医药卫生—眼科]