机构地区:[1]南方医科大学南方医院神经内科,广东省广州市510515
出 处:《中国临床康复》2006年第26期19-22,i0001,共5页Chinese Journal of Clinical Rehabilitation
基 金:国家自然科学基金资助项目(30270468)~~
摘 要:目的:利用掩蔽启动范式和事件相关电位时空模式考察阈上与阈下呈现条件下的情感启动词对后续情感靶词的启动效应。方法:实验于2005-09/10在南方医科大学南方医院完成。以23名健康大学生自愿者为观察对象,无精神疾患以及精神病家族史,(矫正)视力正常。①选取常用名词和形容词1355个按5点记分进行情绪效价(正性、中性、负性)及熟悉度(主观词频)评分,进一步选择高熟悉度及情感效价处于极性分布两端及居中的词汇各60个,分别定义为正性、负性及中性情感词汇,并制作成刺激图片,以汉字笔画叠加后的图片作为启动词的掩蔽刺激。②启动词与靶词构成协调(正-正,负-负);冲突(负-正,正-负);不相关(中-正、中-负)3种关系。③被试任务是注意被掩蔽的启动词后呈现的靶词(呈现300ms),对其情感效价以左、右手按键做出判断,启动与靶词的刺激起始异步分别是600ms和693ms。对反应时间采用2(启动呈现:阈下-11.7ms、阈上-105ms)×3(启动与靶词关系:协调、冲突、不相关)×2(靶词效价:正性、负性)三因素重复测量方差分析;分别在两种启动呈现方式下,对事件相关电位行3(启动与靶词关系)×2(靶词效价)双因素重复测量方差分析,利用F值的统计参数映像呈现分析结果:①交互效应(情绪启动×靶词)。②靶词效应(正/负性)。③情绪启动效应(协调/冲突/不相关)。结果:23名受试者中有5名因脑电干扰太大或高感受性(d’)而被剔除,余18名的测试结果进入统计分析。①反应时间:正性靶词和负性靶词的反应时间分别为(628.59±13.32)ms和(639.58±12.26)ms,差异具有显著趋势[F(1,17)=4.25,P=0.055];而觉察因素和情感启动关系因素均未见显著效应。②事件相关电位的F值统计参数映像:阈下条件下,提示显著交互效应出现于双侧额顶区和左半球(150~200ms);显著靶效应出现于左额颞区(120~150ms)、右半球(20AIM: To investigate neural processing of emotional target words proceded by masked affective priming words presented in either subliminal or supraliminal condition, with the masked priming paradigm and event-related potential (ERP) spatiotemporal pattern. METHODS: The experiment was conducted at Nanfang Hospital of Southern Medical University between September or October in 2005. Without any suffering or family history of mental disorder, 23 college students with normal or corrected sight were volunteered to participate the observation.①Totally 1 355 common nouns or adjectives were collected for scoring emotional valence (positive, neutral, negative) and familiarity (frequencies of subjective words) by 5 ranks. Then 60 words of high familiarity and dis- tributed affective valence were further selected for three emotional categories of positive, negative and neutral on Chinese double-character words (presentation duration: 300 ms), which was proceeded by masked primes.② There were three relations between prime and target: congruent (positivepositive, negative-negative); incongruent (negative-positive, positive-negative); neutral (neutral-positive, neutral-negative).③The stimulus onset asynchrony between prime and target was 600 ms and 693 ms separately. The three-way 2 (prime presentation: subliminal-11.7 ms, supraliminal-105 ms) ×3 (prime-target valence relations: congruent, neutral, incongruent)×2 (target valence: positive, negative) analysis of variance (ANOVA) of repeatedmeasures was performed for reaction time. And the two-way 3 (prime-target relations)×2 (target valence) ANOVA of repeated-measures was performed twice for ERP in beth subliminal and supraliminal presentations separately. The resultant F-value was interpolated to generate statistical parametric mapping (SPM):①interaetion (affeetive primingxtarget)②target effect (positive/negative)③affeetive priming (congruent/incongruent/neutral). RESULTS: Five
分 类 号:R338.8[医药卫生—人体生理学]
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