Buschke-Lowenstein瘤的研究现状  

Buschke-Lowenstein Tumor

作　　者：侯存军[1] 李中伟[1] 

机构地区：[1]山东省皮肤病性病防治研究所,济南250022

出　　处：《国际皮肤性病学杂志》2006年第4期244-246,共3页International Journal of Dermatology and Venereology

摘　　要：Buschke-Lowenstein瘤是生长在肛门、外生殖器的一种巨大赘生物,对其概念的理解曾存在分歧,目前多认为,包含巨大尖锐湿疣和疣状癌两种疾病。病理表现以良性表现为主,但部分病例在大的赘生物中散在小恶变病灶。临床诊断并不困难,关键是要确定是否有恶性变。治疗以手术为主,可配合化疗,以降低复发率。对较小和复发病灶,CO_2激光治疗是一种有效方法。Buschke-Lowenstein tumor is a kind of giant neoplasm,arising from the anus or external genitals. There are many conflicts about the concept of Buschke-Lowenstein tumor. At present, most authors consider it includes giant condyloma acuminata and verrucous carcinoma. Pathological examination shows benign changes in most cases, but at times cancer cells can be detected in some giant neoplasms. Clinical diagnosis is not difficult, nevertheless, to determine the presence of malignanct changes or not is the key of the diagnosis. Its major management is surgical operation, and chemotherapy may be combined to reduce recurrence. CO2 laser therapy is a good choice for minor or recurrent foci.

关 键 词：Buschke—Lowenstein瘤 尖锐湿疣 类乳头状瘤病毒 人 癌 鳞状细胞 

分 类 号：R739.5[医药卫生—肿瘤]