涎腺肌上皮瘤的临床病理分型和免疫组化研究  

Clinical Pathological Classification and Immunohischemistry Study of Myoepithelioma of Salivary Gland

作　　者：王丽京[1] 朱任之[1] 

机构地区：[1]兰州医学院口腔系

出　　处：《兰州医学院学报》1996年第4期3-6,共4页Journal of Lanzhou Medical College

摘　　要：对从1873例涎腺肿瘤复查后确诊的43例涎腺肌上皮瘤进行了临床病理学和免疫组化研究。结果显示:该瘤的发病率约占涎腺肿瘤的2.3％,好发于腮腺(48.84％)和腭腺(41.86％);该瘤在病理上可分为五型:即上皮细胞型、梭形细胞型、浆细胞样细胞型、透明细胞型和混合细胞型,其实质细胞—肿瘤性肌上皮细胞为一个连续变化的瘤细胞谱,各种形态的瘤细胞可以互相转化;免疫组化CK—18、actin染色显示上述各型瘤细胞均为程度不等的阳性。作者认为提高该瘤确诊率的关键是对各型瘤细胞的认识;联合应用CK-18、actin有助于该瘤的诊断和与多形性腺瘤的鉴别。43 cases myoepithlioma of salivary gland , which were confirmed through histological reexamination of the 1873 cases of salivary gland tumors, were studied with clinical pathological and immunohistochemical method. The results showed that this tumor' s morbidity constituted about 2. 3% of the salivary gland tumor. The tumor usually occurred in parotid gland (48. 84%) and palatine glands (41. 86%). It could be classified into five types on the basis of histopathology; Epithelial cell, Spindle cell ,Plasmacytoid cell, Clear cell and Mixed cell. Those parenchymal cells , neoplastic myoepithelial cell, are a continuous oncocyte pedigree which appearance of oncocytes might chang with each other. The results of CK-18 and Actin immunohistochemistry indicated various degree of positive expression in five types. It is important that various oncocytes were recognized. Combination use of CK-18 and Actin antibodies is an authetic method to improve confirmed diagnosis rate of the tumor

关 键 词：涎腺肌上皮瘤 病理 分型 免疫组化 

分 类 号：R739.870.2[医药卫生—肿瘤] R739.870.3[医药卫生—临床医学]