视网膜母细胞瘤临床病理分期对患者视力和生命预后的预测价值  

Clinicopathological Classification for the Prognosis of Vision and Life of Retinoblastoma

作　　者：杨红[1] Harald Schilling Rudolf Effert Achim Wessing 

机构地区：[1]华中科技大学同济医学院附属同济医院眼科,武汉430030 [2]德国埃森综合大学眼科医院,德国埃森45122 [3]德国卡塞尔市立医院眼科,德国卡塞尔34112

出　　处：《华中科技大学学报（医学版）》2006年第3期386-388,共3页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

摘　　要：目的探讨视网膜母细胞瘤患者视力和生命预后的分类方法。方法回顾性分析291例视网膜母细胞瘤患儿的297只眼球的病理变化,根据色素上皮-脉络膜分期及视神经浸润分期,并综合相关文献资料总结患者接受后治疗的各种情况及预后。结果大范围的脉络膜浸润和(或)视神经筛板后浸润接受后治疗占所有后治疗的88%,其生存率为90%。结论大范围的脉络膜浸润及视神经筛板后浸润需接受后治疗以提高生存率。Objective To search for a classification of the visual and living prognosis of patients with retinoblastoma. Methods The pathologic changes of primarily enucleated eyes （297） from 291 patients with retinoblastoma were retrospectively analyzed, According to the pigment epithelium-choroid stage and nerve invasion stage, the various events of post-operative therapy and prognosis were summarized and the relative literatures were reviewed. Results The patients with massive choroid invasion and/or post-laminar infiltration were treated, accounting for 88 % of total patients after enucleation. The survival rate was 90 %. Conclusion The post-operative therapy must be carried out if the massive choroid invasion and the post-laminar invasion of nerve occur, in order to increase the survival rate.

关 键 词：视网膜母细胞瘤 预后 

分 类 号：R739.7[医药卫生—肿瘤] R449[医药卫生—临床医学]