脑卒中后抑郁的研究现状及治疗进展  

The current study situation and therapy progress of PSD

作　　者：郝吉莉[1] 周兰兰[1] 

机构地区：[1]安徽医科大学药理学教研室,安徽合肥230032

出　　处：《安徽医药》2006年第7期481-484,共4页Anhui Medical and Pharmaceutical Journal

基　　金：安徽省科技厅年度重点项目(编号:05021005)

摘　　要：脑卒中后抑郁(post stroke depression,PSD)是脑卒中后常见并发症,它延迟神经功能和认知功能恢复,增加病死率,极大地影响了卒中患者的生活质量。目前发病机制仍不清楚,多数学者认为PSD是生物、社会、心理因素共同作用的结果。治疗首选药物治疗,在单一药物治疗欠佳时可加用心理治疗,对于联合治疗无效的重度PSD可选用电惊厥治疗。Post stroke depression（PSD） is a common complication of stroke. It has negative effect on function recovery and increase mortality. What＇s more, it makes patients have poor quality of lives in longer periods of follow-up. The pathophysiological mechanisms remain unclear. Biology ,social and psychological factors are regarded as the main determinants of PSD. Antidepressant is prior to other anti-depression therapies ,and psychotherapy could be combined when necessary. Major depression patients who have poor response to combination therapies can select electroconvulsive therapy（ECT）.

关 键 词：脑血管意外/并发症 抑郁症/病因学 抑郁症/药物疗法 

分 类 号：R749.1[医药卫生—神经病学与精神病学]