复发性口疮患者免疫功能的研究  

Immunofunctional researches of recurrent aphthous ulcer

作　　者：漆明[1] 窦伟[1] 张敬[1] 李晓凤[1] 刘菊年[1] 

机构地区：[1]宁夏医学院附属医院口腔科

出　　处：《宁夏医学杂志》1996年第4期219-221,共3页Ningxia Medical Journal

基　　金：宁夏区科学技术委员会科研基金项目

摘　　要：采用速率散射比浊法、淋巴细胞转化实验、巨噬细胞吞噬实验及间接免疫荧光法对复发性口疮（简称ＲＡＵ）患者免疫功能进行了检测。结果表明：（１）ＲＡＵ患者血清ＩｇＧ、ＩｇＡ、Ｃ４含量高于正常人（Ｐ＞０．０５）。（２）淋巴细胞转化率、巨噬细胞吞噬率均低于正常人（Ｐ＜０．０５）。Ｔ淋巴细胞总数（Ｔ３）低于正常人，抑制性Ｔ细胞（Ｔ８）高于正常人，辅助性Ｔ细胞（Ｔ４）与Ｔ８比值下降（Ｐ＜０．０５）。说明ＲＡＵ患者体液免疫功能增强，细胞免疫水平处于抑制状态。The immune function was tested in 75 cases of recurrent aphthous ulcer (RAU) using rate nephelometry.lymphocyte blastogenetic test,phagocytosis test of macrophages and indirect immunofluorescence.The results showed that (1) IgG, IgA and C 4 in serum of RAU Cases were higher than that of healthy people ( P <0.05);(2) lymphocyte blastogenetic rate,phagocytosis rate of macrophages and T lymphocyte (T 3) of RAU cases were significantly lower than normal ( P <0.05);but suppressor T cell (Ts or T 8) was higher than normal;the rate of helper T cell(Th or T 4)/T 8 was significantly lower than normal

关 键 词：复发性口疮 口腔粘膜溃疡 免疫功能 测定 

分 类 号：R781.503[医药卫生—口腔医学]