红花黄色素对实验性大鼠脑缺血的保护作用  

The Protective effect of Hsy(safflor yellow) on Experimental rats with Cerebralischemia

作　　者：赵金明[1] 刘士君[1] 李伟[1] 李绍华[1] 

机构地区：[1]辽宁省中医研究院药理研究室,沈阳110031

出　　处：《医学综述》2006年第14期F0002-F0002,F0003,共2页Medical Recapitulate

摘　　要：目的研究红花黄色素对实验性脑缺血大鼠的保护作用。方法结扎颈总动脉制备脑缺血模型。检测指标包括脑含水量血浆超氧化物歧化酶(SOD)及丙二醛(MDA)的含量变化。结果红花黄色素显著降低脑缺血模型大鼠脑含水量,减轻脑水肿,升高血浆SOD含量,并降低MDA含量。结论该药对实验性脑缺血大鼠有明显的保护作用。Objective To study the protective effects of Hsy on experimental rats with cerebral ischemia. Methods We ligated common carotid artery to prepare rat models with cerebral ischemia in order to observe the influence of Hsy on the brain water content in the area of cerebral ischemia, MDA and SOD content of plasma. Results Hsy can reduce the content of water content in brain and MDA in plasma obviously, and increase the concent SOD in plasma. Conclusion This medicine has obvious protective effects on experimental cerebral ischemia rats.

关 键 词：红花黄色素 脑缺血 脑指数 脑含水量 血管通透性 

分 类 号：R743[医药卫生—神经病学与精神病学] R285.5[医药卫生—临床医学]