眼眶特发性炎性假瘤的复发因素分析  

Features associated with recurrence of idiopathic orbital inflammatory pscudotumor

作　　者：颜建华[1] 鲁志卿[1] 吴中耀[1] 李永平[1] 陈智聪[1] 毛羽翔[1] 艾思明[1] 杨华胜[1] 

机构地区：[1]中山大学中山眼科中心,广州510060

出　　处：《中国实用眼科杂志》2006年第7期681-684,共4页Chinese Journal of Practical Ophthalmology

基　　金：广东省自然科学基金(编号010748)

摘　　要：目的寻找导致眼眶特发性炎性假瘤复发的相关因素。方法回顾分析我院1978年1月到1999年12月有临床随访资料的209例眼眶特发性炎性假瘤,采用logisics回归多因素与单因素统计学方法,比较复发与未复发病例的临床特点。结果随访时间半年到21年(平均3.4年),随访结果示复发率为41%,性别、眼球突出度与复发相关。男性比女性容易复发,男性复发率为52%,女性25%;眼球突出度越重,复发率越高;临床类型中,泪腺型的复发率最低,为17%,弥漫型为最高,达100%,其它类型为前眶占位44%,后眶占位54%,肌炎型75%,但多因素分析显示临床类型与复发相关。年龄、眼别、眼睑或结膜充血、眼部疼痛、病理类型、治疗方法和发病时间等均未显示与复发发生相关。结论男性患者、眼球突出度高的病人易于复发;临床亚型中的弥漫型与肌炎型复发率高,但统计学分析未显示与复发相关。Objective To explore factors which lead to recurrence of idiopathic orbital inflammatory pseudotumor （IOIP）, Methods 209 cases of idiopathic orbital inflammatory pseudotumor seen between Jan 1, 1978 and Dec 31,1999 in our hospital were evaluated retrospectively. The comparison of clinical and pathological parameters between patients with at least one episode of recurrence and those with no recurrence at all was performed and analyzed using Logistic Regression method. Results Follow-up results （with a mean follow-up time of 3.4 years, ranging from 0.5 year to 21.0 years） showed that the recurrence rate of IOIP was 41%. Sex and proptosis were associated with recurrent IOIP. Male gender was more likely to relapse than female counterparts, with the male being 52% and female 25%. The severer the proptosis, the higher the rate of recurrence. Among the clinical subtypes of IOIP, the rate of recurrence （17%） in cases with dacryoadinitis was the lowest, followed by anterior local orbital mass （44%）,posterior orbital mass （54%） ,myositis （75%） and diffuse subtype （100%）. However, the clinical subtypes did not show significant relationship with the recurrence of IOIP. Conclusions Male gender and severe proptosis are associated with a higher recurrent rate in patients with IOIP.

关 键 词：眼眶 特发性炎性假瘤 治疗 复发 

分 类 号：R739.72[医药卫生—肿瘤] R749.3[医药卫生—临床医学]