小肝癌的射频消融治疗  

Radiofrequency ablation in the treatment of small liver cancer

作　　者：黄健清[1] 刘海鹰[1] 胡伟民[1] 崔书钟[1] 唐云强[1] 李建昌[1] 余南荣[1] 

机构地区：[1]广州医学院附属肿瘤医院腹外科,广东广州510095

出　　处：《中国普通外科杂志》2006年第6期449-451,共3页China Journal of General Surgery

基　　金：广东省科技厅科研基金项目;粤科计字(2001)281号

摘　　要：目的总结射频消融(RFA)治疗肿瘤直径≤5 cm小肝癌的疗效和经验。方法从1 9 9 9年9月-2 0 0 5年5月期间,采用RFA治疗肿瘤直径≤5 cm的原发性或转移性肝癌共1 3 0例,其中原发性肝癌8 6例,转移性肝癌4 4例。1 8例结合肝动脉栓塞化疗,2 0例同时行RFA联合瘤内无水酒精注射术。结果1,3年总累积存活率分别为9 1.3%,7 7.7%。治疗中7例发生并发症,分别为少量胆瘘、肠瘘、轻度皮肤灼伤,未发现与治疗相关的死亡。结论RFA对肿瘤直径≤5 cm的小肝癌是一种相对安全、有效的治疗方法,并有可能达到与手术切除相似的效果。Objective To investigate the effect of radiofrequency ablation （ RFA ） in the treatment of small liver cancer. Methods In recent 6 years, 130 patients with primary or secondary liver cancer （ ≤ 5 cm in diameter） were treated by RFA, among which 86 cases were primary, and 44 cases were secondary liver cancer. Among the 130 cases, l 8 received RFA plus TAEC, and 20 had RFA combined with PEI. Results Overall 1- and 3-year survival rate was 91. 3 % and 77. 7 % respectively. Complications occurred in 7 cases, including biliary fistula, intestinal fistula, and slight burn of skin. There was no death in this series. Conclusions RFA is an effective and safe therapeutic approach for small liver cancer ≤5 cm in diameter. Its effect may be similar to that of surgical resection.

关 键 词：肝肿瘤/治疗 射频热毁损 栓塞 治疗性 注射 病灶内 

分 类 号：R735.7[医药卫生—肿瘤]