肝炎肝硬化并发自发性细菌性腹膜炎治疗探讨  

The study on therapy for viral hepatitis-related hepatocirrhosis with spontaneous bacterial peritonitis.

作　　者：何长伦[1] 隋云华[1] 汪朝晖[1] 韩振红[1] 

机构地区：[1]南京市解放军第八一医院南京军区肝病研究所,210002

出　　处：《实用肝脏病杂志》2006年第4期233-234,共2页Journal of Practical Hepatology

摘　　要：目的探讨肝炎肝硬化并发自发性细菌性腹膜炎的治疗。方法147例肝炎肝硬化并发自发性细菌性腹膜炎患者行综合治疗:1积极支持治疗;2舒普深抗感染,每日4克,共3周;3每次放腹水后使用罗氏芬1克,腹腔注射。同期另118例肝炎肝硬化并发自发性细菌性腹膜炎患者,接受积极支持治疗和舒普深抗感染,每日4克,共2周。结果与对照组比,抗感染3周疗程加放腹水组患者腹水消退快,总胆红素下降明显,腹腔感染控制较彻底,一年后自发性细菌性腹膜炎复发率显著降低(P<0.05)。结论肝炎肝硬化并发自发性细菌性腹膜炎的抗感染治疗疗程要长,适时放腹水可提高疗效。Objective To study the therapy for viral hepatitis-related hepatocirrhosis with spontaneous bacterial peritonitis （SBP）. Methods 147 patients with SBP were treated by combined therapy.. 1 ,supportive therapy actively; 2, antibacterial treatment with cefoperazone sodium and sulbactam sodium at 4g daily for 21 days; and 3, ceftriaxone sodium 1g was injected into abdominal cavity after ascites being drowned. Another 118 patients with SBP received supporting and antibacterial treatment for 2 weeks. Results The ascites removed, total serum bilirubin improved and infection controlled in the 3-week regimen,much superior to the 2-week treatment （P〈0. 05）. Conclusion The treatment for SBP in patients with viral hepatitis--related hepatocirrhosis must be long enough to maintain the curative effectiveness.

关 键 词：肝炎肝硬化 自发性细菌性腹膜炎 抗感染治疗 

分 类 号：R575.2[医药卫生—消化系统] R733.71[医药卫生—内科学]