丁螺环酮、百忧解加心理治疗对抑郁症的疗效对比研究  

Matched control study on curing melancholia by using Buspirone and PROZAC combined with psychological treatment

作　　者：罗来兴[1] 黄嫦娥[2] 张秀芳[2] 

机构地区：[1]惠州市第二人民医院,516001 [2]惠州市中心人民医院

出　　处：《神经疾病与精神卫生》2006年第3期198-199,共2页Journal of Neuroscience and Mental Health

摘　　要：目的探讨丁螺环酮合并百忧解加心理治疗对抑郁症的临床效果。方法随机将60例抑郁症患者分为药物对照组和合用研究组,经过8周的治疗。以汉密顿抑郁量表(HAMD)评定疗效,以不良反应症状量表(TESS)评定副反应。心理治疗采用认知疗法。结果HAMD疗前疗后和两组间2、4、6、8周评分均有显著性差异。两组TESS评分各周均没有统计学意义。药物加心理治疗组的疗效好于药物组,差异显著。结论丁螺环酮合并百忧解加心理治疗抑郁症的疗效好,起效快,治疗时间短,疗效持久不易复发。Objective To discuss the curative effect of Buspirone and PROZAC combined with psychological treatment on melancholia. Methods Melancholia patients were randomly divided into two groups., drug control group, and combination study group. The treatment lasted for eights weeks. HAMD was used to assess curative effect and TESS for side effect. Cognitive therapy was used in psychological treatment. Results There was statistical significance between pre- and post-treatment group, and it was the same between random two groups that come from two, four, six and eight weeks after treatment. There was no statistical significance between every week TESS Score group. The effect of study group is better than the control group, and the difference is significant. Conclusions Buspirone and PROZAC combined with psychological treatment is effective on melancholia patient and would reduce relapse.

关 键 词：抑郁症 丁螺环酮 百忧解 认知疗法 

分 类 号：R749.4[医药卫生—神经病学与精神病学]