前列腺癌危险因素的病例对照研究  

A Case-control Study of Prostate Cancer

作　　者：杜树发[1] 施侣元[1] 何尚浦[1] 张惠娟[1] 张兆强[2] 左建明 

机构地区：[1]同济医科大学流行病学教研室,武汉430030 [2]山东省济宁医学院 [3]湖北省武汉市生物制品研究所

出　　处：《中华流行病学杂志》1996年第6期343-345,共3页Chinese Journal of Epidemiology

摘　　要：笔者采用1:1配比的病例对照研究方法,对前列腺癌的危险因素进行了研究。以前列腺癌现患病人作为病例,所有病例均经病理切片诊断,对照配比条件为病例的邻居、年龄±5岁。对照不包括前列腺增生患者和肿瘤患者。共调查102对病例和对照,对调查表中86个因素进行了单因素分析和条件Logistic回归分析,结果表明,高体质指数、泌尿系统病史、子女数多于3个、青壮年期每周性交超过3次、滥用性药物等因素是前列腺癌的危险因素,体力劳动、初次遗精年龄晚于18岁等因素对前列腺癌的发生有一定的保护作用。In America and many European countries, prostate cancer is the most common cancer and the second leading cause of cancer death in men. Among 10-30% of all the men older than 50 years of age ,a silent microscopic form of prostate cancer may be harbored. This high rate is similar throughout the world. However, few epidemiologic studies of prostate cancer have implicated its risk factors. A 1:1 matched case control study looked into risk factors of prostate cancer. A total number of 102 cases of prostate cancer and 102 controls were surveyed. The results showed that high body mass index, history of urinary diseases, coitus frequency>3 times per week, hormone drug use, and number of children>3 are identified as risk factors of prostate cancer statistically, but physical labor, exercise, and age of first nocturnal emission>18 are protective factors of prostate cancer.

关 键 词：前列腺肿瘤 危险因素 病例比较研究 

分 类 号：R737.25[医药卫生—肿瘤]