60例鼻咽非霍奇金淋巴瘤的预后因素分析  

Analysis of prognostic factors on 60 patients with nasopharyngeal non-Hodgkin′s lymphomas

作　　者：熊莉 张灿珍[2] 任宏轩[2] 沈丽达[2] 张晓娟[2] 

机构地区：[1]湖南省湘西土家族苗族自治州人民医院肿瘤科,湖南吉首416000 [2]云南省肿瘤医院肿瘤内一科,云南昆明650118

出　　处：《现代肿瘤医学》2006年第8期1004-1006,共3页Journal of Modern Oncology

摘　　要：目的:探讨影响鼻咽非霍奇金淋巴瘤预后的因素。方法:对60例鼻咽非霍奇金淋巴瘤的临床特征、治疗和初次疗效等因素,进行Kap lan-M e ier生存分析和COX回归分析。结果:Kap lan-M e ier分析示:年龄、B症状、临床分期、淋巴结受累、免疫分型、LDH、治疗及初次疗效均影响患者的生存,COX回归显示:临床分期、淋巴结受累、免疫分型、LDH、治疗和初次疗效是影响预后的独立因素。结论:对鼻咽非霍奇金氏淋巴瘤进行综合治疗,首程治疗达完全缓解可改善预后,针对患者的预后因素进行个体化治疗是必要的。Objective：To discuss the prognostic factors on nasopharyngeal non -Hodgkin＇s lymphomas. Methods： In 60 patients with nasopharyngeal non-Hodgkin＇s lymphomas, Kaplan-Metier survival analysis and COX regression were administered to analyze some factors such as clinical characteristics , treatment, first effect, etc. Resuits： Kaplan - Metier survival analysis showed that age, B symptom, clinical stage, state of lymph node, immune category, LDH, treatment and fn＇st effect, were the prognostic factors on nasopharyngeal non-Hodgkin＇s lymphomas;and COX regression showed only clinical stage, state of lymph node, immune category, LDH, treatment ,first effect were the independent prognostic factors. Conclusion： Synthetic treatment and complete response of first effect may improve the prognosis of nasopharyngeal non-Hodgkin＇s lymphomas, individualization therapy is very essential.

关 键 词：鼻咽非霍奇金淋巴瘤 预后 生存分析 

分 类 号：R730.263[医药卫生—肿瘤]