A pilot randomized control study to evaluate endoscopic resection using a ligation device for rectal carcinoid tumors  

作　　者：Hiroyuki Sakata Ryuichi Iwakiri Akifumi Ootani Seiji Tsunada Shinichi Ogata Hibiki Ootani Ryo Shimoda Kanako Yamaguchi Yasuhisa Sakata Sadahiro Amemori Kotaro Mannen Masanobu Mizuguchi Kazuma Fujimoto 

机构地区：[1]Department of Internal Medicine Saga Medical School,Saga 849-8501,Japan [2]Department of Radiology Saga Medical School,Saga 849-8501,Japan

出　　处：《World Journal of Gastroenterology》2006年第25期4026-4028,共3页世界胃肠病学杂志（英文版）

摘　　要：AIM： Rectal carcinoid tumors smaller than 10 mm can be resected with local excision using endoscopy. In order to remove rectal carcinoid tumors completely, we evaluated endoscopic mucosal resection with a ligation device in this pilot control randomized study. METHODS： Fifteen patients were diagnosed with rectal carcinoid tumor （less than 10 mm） in our hospital from 1993 to 2002. There were 9 males and 6 females, with a mean age 61.5 years （range, 34-77 years）. The patientshad no complaints of carcinoid syndrome symptoms. Fifteen patients were randomly divided into 2 groups： 7 carcinoid tumors were treated by conventional endoscopic resection, and 8 carcinoid tumors were treated by endoscopic resection using a ligation device. RESULTS： All rectal carcinoid tumors were located at the middle to distal rectum. The size of the tumors varied from 3 mm to 10 mm and background characteristics of the patients were not different in the two groups. The rate of complete removal of carcinoid tumors using a ligation device （100%, 8/8） was significantly higher than that of conventional endoscopic resection （57.1%, 4/7）. The three patients had tumor involvement of deep margin, for which additional treatment was performed. No complications occurred during or after endoscopic resection using a ligation device. All patients in the both groups were alive during the 3-year observation period. CONCLUSION： Endoscopic resection using a ligation device is a useful and safe method for resection of small rectal carcinoid tumors.瞄准：比 10 公里小的直肠的良性肿瘤肿瘤能是有用内视镜检查法的本地切除的 resected。以便完全移开直肠的良性肿瘤肿瘤，我们在这飞行员控制与一台结扎设备评估了内视镜的粘膜切除术使随机化的学习。方法：十五个病人从 1993 ～ 2002 在我们的医院里与直肠的良性肿瘤肿瘤(不到 10 公里) 被诊断。有 9 男性和 6 女性，与吝啬的年龄 61.5 年(范围， 34-77 年) 。病人没有良性肿瘤症候群症状的抱怨。十五个病人随机被划分成 2 个组：7 个良性肿瘤肿瘤被常规内视镜的切除术治疗，并且 8 个良性肿瘤肿瘤被内视镜的切除术用一台结扎设备治疗。结果：所有直肠的良性肿瘤肿瘤在中间被定位到远侧的直肠。从 3 公里改变到 10 公里和病人的背景特征的肿瘤的尺寸不在二个组是不同的。用一台结扎设备的良性肿瘤肿瘤的完全的移动的率(100% ， 8/8 ) 比常规内视镜的切除术的显著地高(57.1% ， 4/7 ) 。三个病人有深边缘，另外的治疗为被执行的肿瘤参与。没有复杂并发症用一台结扎设备发生了在期间或在内视镜的切除术以后。在两个组的所有病人在 3 年的观察时期期间是活着的。结论：用一台结扎设备的内视镜的切除术是为小直肠的良性肿瘤肿瘤的切除术的一个有用、安全的方法。

关 键 词：CARCINOID Ligation mucosectomy ENDOSCOPY RECTUM Conventional method 

分 类 号：R735.37[医药卫生—肿瘤]