Cyclotrimerization of Aliphatic Aldehydes Catalyzed by Ionic Liquids  

作　　者：于心玉 刘彩华 杨建国 何鸣元 

机构地区：[1]Shanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, Shanghai 200062

出　　处：《Chinese Journal of Chemistry》2006年第8期1066-1068,共3页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China（No. G2000048）.

摘　　要：Aliphatic aldehydes such as ethanal, propanal, n-butanal, isobutyraldehyde, n-valeraldehyde, isovaleraldehyde, n-hexanal and n-octanal were converted into the corresponding 2.4,6-trialkyl-1,3,5-trioxanes through cyclotrimerization in the presence of the ferric chloride based ionic liquids at room temperature without solvent in high selectivity. The effects of different ionic liquids, acidity of ionic liquids and temperature on cyclotrimerization were also studied. The results showed that the ferric chloride based ionic liquids （apparent molar fraction of FeCl3 （x（FeCl3）= 0.62）） were a kind of efficient catalysts for the cyclotrimerization of aliphatic aldehyde which could be separated conveniently from the reaction mixture and recycled without loss of catalytic activity. The conversion of isobutyraldehyde and the selectivity to 2,4,6-triisopropyl-1,3,5-trioxane were 91.1% and 99.8% respectively under optimum reaction condition （isobutyraldehyde 25.0 g, [Et3NH]Cl/FeCl3 （x（FeCl3）=0.62） 1.0 g, 25 ℃ for 1 h）.Aliphatic aldehydes such as ethanal, propanal, n-butanal, isobutyraldehyde, n-valeraldehyde, isovaleraldehyde, n-hexanal and n-octanal were converted into the corresponding 2.4,6-trialkyl-1,3,5-trioxanes through cyclotrimerization in the presence of the ferric chloride based ionic liquids at room temperature without solvent in high selectivity. The effects of different ionic liquids, acidity of ionic liquids and temperature on cyclotrimerization were also studied. The results showed that the ferric chloride based ionic liquids （apparent molar fraction of FeCl3 （x（FeCl3）= 0.62）） were a kind of efficient catalysts for the cyclotrimerization of aliphatic aldehyde which could be separated conveniently from the reaction mixture and recycled without loss of catalytic activity. The conversion of isobutyraldehyde and the selectivity to 2,4,6-triisopropyl-1,3,5-trioxane were 91.1% and 99.8% respectively under optimum reaction condition （isobutyraldehyde 25.0 g, [Et3NH]Cl/FeCl3 （x（FeCl3）=0.62） 1.0 g, 25 ℃ for 1 h）.

关 键 词：aliphatic aldehyde CYCLOTRIMERIZATION 2 4 6-trialkyl-1 3 5-trioxane ionic liquid 

分 类 号：O623.425[理学—有机化学]