2－硫代磷酸酯基－3，4－二氢呋喃并喹啉化合物的合成和抑菌活性  

Synthesis and Bioactivity of Some 2-Thiophosphate-3,4-Dihydrofuroquinolines

作　　者：刘准[1] 李树正[1] 米中茂 张春香[1] 孙莹[1] 

机构地区：[1]南开大学元素有机化学研究所

出　　处：《应用化学》1996年第5期14-16,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金

摘　　要：６－取代基－２－氧－３，４－二氢呋喃并喹啉类化合物用氢化钠还原所生成的醇钠与硫代磷酰氯缩合制备３，４－二氢呋喃并喹啉化合物，通过￣１ＨＮＭＲ，ＭＳ和元素分析鉴定了它们的结构，并初步测试了它们的抑菌活性．Ten new title compounds were synthesized by condensation of thiophosphoryl chlorides and 2-sodium alcoholate-6-substitutent-3, 4-dihydrofuroquinolines, the latter being prepared from the reduction of corresponding 2-oxo compounds with sodium hydride. Their structures were confirmed by ￣1H NMR, MS, and elemental analysis. Some of them have good antifungous activity to pellicularia sasakii of rice.

关 键 词：二氢呋喃并喹啉 硫代磷酸酯 抑菌活性 

分 类 号：O626.323[理学—有机化学] TQ455.47[理学—化学]