β－环糊精衍生物的合成及对脲酶的抑制作用  

SYNTHESIS OF THE β CYCLODEXTRIN DERIVATIVE AND ITS INHIBITION ACTION ON UREASE

作　　者：丁志刚[1] 任维衡[1] 习玲玲 罗天顺[1] 宋发军[1] 

机构地区：[1]中南民族学院化学系

出　　处：《催化学报》1996年第6期567-569,共3页

基　　金：湖北省科委基金

摘　　要：β┐环糊精衍生物的合成及对脲酶的抑制作用＊丁志刚任维衡习玲玲罗天顺宋发军（中南民族学院化学系，武汉４３００７４）关键词β－环糊精，衍生物，脲酶，配合物近年来，随着生物医学工程的迅速发展，新型医用级吸附树脂的研制取得了较大进步．其中有关铵离子和尿素的吸...Two β cyclodextrin derivatives, bis(6 O butene diacid ester) β cyclodextrin (compound 1) and bis[6 O (3 deoxy citric ester)] β cyclodextrin (compound 2), were synthesized by reaction of β cyclodextrin with maleic anhydride and chloroacetic acid in succession. It was found that the compound 2 could inhibit the activity of urease for the urea hydrolysis by 15%, and the activity of the urease could be recovered by adding FeCl 3 solution. It was also found that the complex formed by Fe 3+ and the compound 2 could act as a mimic enzyme to catalyze the oxidation of toluene to benzaldehyde and benzoic acid.

关 键 词：Β-环糊精 衍生物 脲酶 配合物 

分 类 号：O636.12[理学—高分子化学]