鸡基因组计划及在遗传学研究中的应用  

Chicken Genome Project and Its Application in Genetic Research

作　　者：赵心怡[1] 杨威[2] 张勇[2] 朱大海[1] 

机构地区：[1]哈尔滨工业大学生命科学与工程系分子与细胞发育生物学实验室,哈尔滨150001 [2]中国协和医科大学基础医学院生物化学与分子生物学系医学分子生物学国家重点实验室,北京100005

出　　处：《遗传》2006年第8期1002-1008,共7页Hereditas（Beijing)

摘　　要：鸡,以其独特的生物学特性,成为研究许多生物学问题的重要模式生物。而在长期选育中形成的肉鸡和蛋鸡两大品系/种则是研究许多遗传性状的分子机制的理想模型。鸡基因组计划的完成,极大推动了以鸡作为模式生物的研究与利用。文章重点介绍了鸡基因组学的研究进展,和利用基因组相关信息对鸡的不同品种数量性状进行遗传学研究的方法策略;并阐明了以鸡作为模式生物,利用基因组学的信息进行发育和遗传学研究的广阔前景。Chicken is an important model organism for studying all sorts of biological problems due to its unique biological features. Two strains of chicken, the egg-laying layer and meat-producing broiler, which were generated from selective breeding, come to be ideal models for understanding the molecular mechanisms underlying different phenotypes. The Chicken Genome Project provides a large amount of information for research using chicken as the model. This review summarizes the development of the Chicken Genome Project, as well as the strategies for researching the quantitative traits of different chicken strains using the information of the Chicken Genome. We also give a perspective of the developmental and genetic studies that can be conducted using the chicken as a model organism as well as using its genomic information.

关 键 词：鸡 基因组 肉鸡和蛋鸡 基因组作图 

分 类 号：S831[农业科学—畜牧学] Q953[农业科学—畜牧兽医]