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作 者:叶翠玉[1] 沙翔垠[1] 姚达强[1] 郭露萍[1] 李玥瑶[1] 丁宇虹[1] 刘咏仪[1]
机构地区:[1]广州医学院第二附属医院眼科,广东广州510260
出 处:《广州医学院学报》2006年第2期54-56,63,共4页Academic Journal of Guangzhou Medical College
摘 要:目的:观察准分子激光角膜原位磨镶术(laser in situ keratom ileusis,LASIK)后泪膜功能的改变,探讨LASIK术后发生眼干现象的原因。方法:对广州医学院第二附属医院眼科100例近视患者186只眼进行LASIK手术,分别测定其术前,术后1周、1个月、3个月的泪液分泌量(用Sch irm er I实验测定)、泪膜破裂时间(break-up tim e,BUT)和角膜荧光素染色试验。结果:①Sch irm er I值:术前为(15.89±6.70)mm,术后1周为(12.08±7.30)mm,术后1月为(10.43±5.52)mm,术后3月为(11.56±6.82)mm。②平均BUT值:术前为(12.83±5.04)s,术后1周为(9.07±6.40)s,术后1月为(8.74±7.56)s,术后3月为(10.23±5.76)s。③术后1周角膜荧光素染色比术前加重。结论:LASIK术后早期可导致泪膜稳定性下降,泪液分泌减少,产生干眼症状,主要原因可能与术后角膜知觉减退有关。Objective: To observe the changes in the function of tear film after laser in situ keratomileusis (LASIK) for myopia. Methods: One hundred myopic patients (186 eyes) treated with LASIK were evaluated for tear flow (Schirmer I test), tear break-up time (BUT) tests and fluorescein staining scores before operation and at 1 week, 1 month and 3 month intervals after the operation. Results: (1) the mean values of Schirmer I were (15.89 ±6.70) mm preoperatively; ( 12.08 ±7.30) mm, ( 10.43 ±5.52) mm, ( 11.56 ±6.82) mm at 1 week, 1 month and 3 months postoperatively ( P 〈 0.05 ). ( 2 ) The mean BUT were ( 12.83 ± 5.04 ) seconds preoperatively, ( 9.07 ± 6.40 ) seconds, (8.74 ± 7.56) seconds and ( 10.23 ± 5.76) seconds at 1 week, 1 month and 3 months postoperatively ( P 〈 0.05 ). ( 3 ) The FL staining was intensified at 1 week postoperatively as compared with before operation. Conclusion: LASIK caused a decrease in tear film stability and tear secretion early stage after operation, probably due to decreased corneal sensation after LASIK.
关 键 词:泪液分泌值 泪膜稳定性 准分子激光原位角膜磨镶术(LASIK)
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