脑原发性淋巴瘤的CT和MRI诊断  

CT and MRI diagnosis and differentiation of primary brain lymphoma

作　　者：于昭[1] 李胜凯[1] 范伟雄[1] 于靖[1] 林优[1] 邹敏[1] 

机构地区：[1]梅州市人民医院放射科,广东省梅州514031

出　　处：《中国基层医药》2006年第7期1158-1160,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的总结分析脑原发性淋巴瘤的影像学表现特征。方法回顾性分析3例经病理证实的脑原发性淋巴瘤的临床病理资料和CT、MRI表现。结果本组脑内多发病变2例,单发1例。CT表现:多发者表现为双侧额、顶叶皮层下深部白质区、双侧基底节区及丘脑散在分布的大小不等稍高密度结节或肿块,均明显强化;单发者右丘脑部明显肿胀,内见高低混杂密度影,呈多结节及肿块样强化,周围见明显水肿带。MRI表现:多发者表现为稍长T1、T2信号结节,大小不等,形状不一。单发者T1/WI为等-低混杂信号,T2/WI为高-低混杂信号。呈大小不等结节及肿块样强化。结论虽然脑原发性淋巴瘤术前影像诊断困难,但其发病部位及影像学表现具有一定的特异性,仔细分析其特点并结合临床表现及病程,可以作出正确的诊断。Objective To analyze CT and MRI image in patients suffering primary central nervous system lymphoma（PCNSL）. Methods A retrospective analysis of the clinical datas and CT/MRI image was carried out in a group of 3 patients pathologically diagnosed as PCNSL. Results Lesions in cerebral parenchyma were confirmed in all the 3 cases including 2 for multiple lesions and 1 for solitary lesion. CT findings： CT images of patients with multiple lesions show nonuniform hyper-dense nodular or massive lesion in the deep white matter subcortical located in the bilateral frontal lobes and parital lobes, in the bilateral basal nucleus and thalamies, all of which were highly enhanced. As for the patient with solitary lesion, a mixture of hyper-dense and hypo-dense was identified in the swollen right thalamencephalon. Nodular or massive lesion was surrounded by clear edema in the enhanced image. MRI findings ： nonuniform polymorphous nodular lesions with longish T1 and T2 signals were exhibited in patients with multiple lesions. As for the patient with solitary lesion, isointense/hypointense signals on T1/WI images and hyperintense/ hypointense signals on T2/WI images were found. Nonuniform nodular/massive lesion was exhibited in the enhanced scan. Condusion Although it is difficult to give a presurgical diagnosis for PCNSL by means of radiological examination, the information provided by the imaging scanning such as the site of foci and other imaging manifestation still has some specificity. Therefore,it is passible to give a definite diagnosis after analyzing these imaging manifestation and clinical data carefully.

关 键 词：脑 淋巴瘤 计算机体层摄影 磁共振成像 病理学 

分 类 号：R739.4[医药卫生—肿瘤]