吡哆醇二棕榈酸酯的合成  

Synthesis of pyridoxine dipalmitate

作　　者：郭雪飞[1] 廖发盆[1] 黄小华[1] 

机构地区：[1]东北林业大学化学系,黑龙江哈尔滨150040

出　　处：《应用化工》2006年第7期532-534,共3页Applied Chemical Industry

摘　　要：采用吡哆醇与棕榈酸为原料,水溶剂法合成吡哆醇二棕榈酸酯。通过正交实验得到适宜的反应条件为:棕榈酰氯与吡哆醇的质量比为2∶1,反应温度16℃,反应时间20 h,以吡哆醇计产率58.4%,纯度88.9%。This paper tested the process to prepare pyridoxine dipalmitate from pyridoxine and palmitie acid. Water was used as solvent. The process was optimized by orthogonal experiment and a better synthetic condition was obtained. The results showed that quality ratio of aeyl chlorination of palmitie acid to pyridoxine was 2： 1, temperature was 16℃, reaction time was 20 h. The yield was 58.4% and purity was 88.9%.

关 键 词：吡哆醇 棕榈酸 吡哆醇二棕榈酸酯 

分 类 号：TQ031.2[化学工程] TQ225.24