年龄相关性黄斑变性患者经光动力治疗后光学相干断层扫描检查的早期变化  

Early optical coherence tomography changes after photodynamic therapy in patients with age-related macular degeneration

作　　者：Ozdemir H. Karacorlu S.A. Karacorlu M. 王永强(译) 

机构地区：[1]不详 [2]Istanbul Retina Institute Inc., K. 7, Hakki Yeten Caddesi, No. 8, 34349 Sisli-lstanbul, Turkey

出　　处：《世界核心医学期刊文摘（眼科学分册）》2006年第6期13-14,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：PURPOSE: To evaluate early changes after photodynamic therapy (PDT) in patients with age-related macular degeneration (AMD) by optical coherence tomography (OCT). DESIGN: Prospective interventional case series. METHODS: PDT was performed on 20 eyes of 20 patients who presented with subfoveal choroidal neovascularization (CNV) attributable to AMD. OCT was used to evaluate changes at 2,12,and 24 hours and at 3,7,15,and 30 days after therapy. RESULTS: In the first 24 hours,OCT showed an increase in the subretinal fluid (SF) in all eyes and an increase in intraretinal fluid (IF) in 13 eyes. On the 15th day and the 30th day after therapy,reduction of SF and IF was observed in almost all eyes. CONCLUSIONS: Serial OCT evaluation of patients with subfoveal CNV attributable to AMD suggests that the initial response after PDT is an increase in SF and IF.PURPOSE： To evaluate early changes after photodynamic therapy （PDT） in patients with age-related macular degeneration （AMD） by optical coherence tomography （OCT）. DESIGN： Prospective interventional case series. METHODS： PDT was performed on 20 eyes of 20 patients who presented with subfoveal choroidal neovascularization （CNV） attributable to AMD. OCT was used to evaluate changes at 2, 12, and 24 hours and at 3, 7, 15, and 30 days after therapy. RESULTS： In the first 24 hours, OCT showed an increase in the subretinal fluid （SF） in all eyes and an increase in intraretinal fluid （IF） in 13 eyes. On the 15th day and the 30th day after therapy, reduction of SF and IF was observed in almost all eyes. CONCLUSIONS： Serial OCT evaluation of patients with subfoveal CNV attributable to AMD suggests that the initial response after PDT is an increase in SF and IF.

关 键 词：年龄相关性黄斑变性 光学相干断层扫描 光动力治疗 早期变化 治疗后 患者 扫描检查 中心凹下脉络膜新生血管 中心凹下CNV CT检查 

分 类 号：R774.5[医药卫生—眼科] R730.5[医药卫生—临床医学]