儿童屈光参差性弱视行屈光性角膜切削术的远期效果  

Long-term outcomes of photorefractive keratectomy for anisometropic amblyopia in children

作　　者：Paysse E. A. Coats D. K. Hussein M. A. W. 王大江(译) 

机构地区：[1]不详 [2]Baylor College of Medicine, Texas Children's Hospital, 6621 Fannin MC CC 640.00, Houston, TX 77030, United States

出　　处：《世界核心医学期刊文摘（眼科学分册）》2006年第6期40-41,共2页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Purpose: To evaluate the long-term visual acuity (VA) and refractive error responses to excimer laser photorefractive keratectomy (PRK) for treatment of anisometropic amblyopia in children. Design: Prospective interventional case-control study. Participants: Eleven children,2 to 11 years old,with anisometropic amblyopia who were noncompliant with conventional therapy with glasses or contact lenses and occlusion therapy were treated with PRK. A cohort derived retrospectively of 13 compliant and 10 noncompliant children with refractive errors similar to those of the PRK group who were treated with traditional anisometropic amblyopia therapy served as control groups. Intervention: Photorefractive keratectomy for the eye with the higher refractive error. Main Outcome Measures: (1) Refractive error reduction and stability in the treated eye,(2) cycloplegic refraction,(3) VA,(4) stereoacuity,and (5) corneal haze up to 3 years after PRK. Compliant and noncompliant children with anisometropia amblyopiawere analyzed as controls for refractive error and VA. Results: Preoperative refractive errors were-13.70 diopters (D) (± 3.77) for themyopic group and + 4.75 D (± 0.50) for the hyperopic group. Mean postoperative refractive errors at last follow-up (mean,31 months) were-3.55 D (± 2.25) and + 1.41 D (± 1.07) for the myopic and hyperopic groups,respectively. At last follow-up,cycloplegic refractions in 4 (50% ) of 8 myopes and all hyperopes (100% ) were within 3 D of that of the fellow eye. Five (63% ) of 8 myopic children achieved a refraction within 2 D of the target refraction. Two (67% ) of 3 hyperopic patients maintained their refractions within 2 D of the target. Refractive regressions (from 1 year after surgery to last followup) were 0.50± 1.41D (myopes) and 0.60± 0.57D (hyperopes). Seven children (77% ) were able to perform psychophysicalVA testing preoperatively and postoperatively. Five (71% ) of the 7 children had uncorrected VA improvement of at least 2 lines,and 4 (57% ) of 7 had best spectacle-corrected VPurpose： To evaluate the long-term visual acuity （VA） and refractive error responses to excimer laser photorefractive keratectomy （PRK） for treatment of anisometropic amblyopia in children. Design： Prospective interventional case-control study. Participants： Eleven children, 2 to 11 years old, with anisometropic amblyopia who were noncompliant with conventional therapy with glasses or contact lenses and occlusion therapy were treated with PRK. A cohort derived retrospectively of 13 compliant and 10 noncompliant children with refractive errors similar to those of the PRK group who were treated with traditional anisometropic amblyopia therapy served as control groups. Intervention： Photorefractive keratectomy for the eye with the higher refractive error. Main Outcome Measures： （1） Refractive error reduction and stability in the treated eye, （2） cycloplegic refraction, （3） VA, （4） stereoacuity, and （5） corneal haze up to 3 years after PRK. Compliant and noncompliant children with anisometropia amblyopiawere analyzed as controls for refractive error and VA.

关 键 词：准分子激光屈光性角膜切削术 屈光参差性弱视 儿童 屈光不正性弱视 远期效果 病例对照研究 PRK手术 近视患者 睫状肌麻痹 治疗方法 

分 类 号：R779.63[医药卫生—眼科] R777.44[医药卫生—临床医学]