晴尔治疗急性脑梗死时FB、PC和BCT变化的临床意义  

Clinical significance of changes of FB,PC and BCT in patients with acute cerebral infarction

作　　者：欧小凡[1] 容琼文[1] 

机构地区：[1]海南医学院附属医院神经内科,海南海口570102

出　　处：《中国热带医学》2006年第8期1460-1461,共2页China Tropical Medicine

摘　　要：目的分析晴尔(奥扎格雷钠)治疗急性脑梗死纤维蛋白原(FB)、血小板(PC)、出凝血时间(BCT)变化的临床意义。方法对34例急性脑梗死患者在常规治疗的基础上应用晴尔,对治疗前后的FB、PC、BCT进行检测,设立对照组。结果治疗组和对照组FB、PC治疗后较治疗前均有明显下降,P值分别<0.01和P<0.05,两组间比较差异呈显著性(P<0.05)。而BCT无明显影响。结论晴尔治疗急性脑梗死可使FB明显下降,有抑制血小板活化的作用,且无出血倾向,显示出晴尔治疗作用的多途径性及安全性。Objective To investigate the change of FB 、 PC 、 and BCT before and after acute cerebral infarction being treated with Sodium Ozagrel. Methods 68 cases acute cerebral infarction were treated with Sodium Ozagrel on the basis of conventional treatment.The FB 、PC and BCT was examined before anf after the treatment.The contrast group was set up. Results The FB、PC of the treatment group and the contrast were more extremely reduced after treatment than before. The value of P was respectively less than 0.01 and 0.05, the contrast between the two groups presented significant difference （ P 〈 0.05）. Conclusion That Sodium Ozagrel treated acute cerebral infarction may have FB obviously fall and have the effect on inhabit activation of platelet and have no hemorrhage incline, this appears that Sodium Ozagrel has a lot of ways in treatment effort and safety.

关 键 词：晴尔(奥扎格雷钠) 急性脑梗死纤维蛋白原 血小板 出凝血时间 

分 类 号：R743[医药卫生—神经病学与精神病学]