Spectrophotometric Study on Some Amino Acid Drugs with Chloranil and its Analytical Application  

作　　者：Sheng Yun LI Yin Zhe REN Feng Lin ZHAO 

机构地区：[1]Department of Chemistry, Taiyuan Normal University, Taiyuan 030001 [2]Department of Chemistry, Shanxi Normal University, Linfen 041004 [3]Department of Chemistry, Peking University, Beijing 100871

出　　处：《Chinese Chemical Letters》2006年第8期1065-1068,共4页中国化学快报（英文版）

摘　　要：The interaction between amino acid drugs, aminobutyric acid, carbocisteine and levodopa, with chloranil was studied spectrophotometrically. The conditions were investigated and optimized. The interaction obeyed Beer＇s law over the range of 0.2-8.7, 1.2-20 and 2-26.4 μg/mL for aminobutyric acid, carbocisteine and levodopa, respectively. The validity was compared with that by the official methods^1,3,5 and the recovery studies of standard addition method, the result is satisfactory. The proposed method has been successfully applied to the determination of the above drugs in tablets.The interaction between amino acid drugs, aminobutyric acid, carbocisteine and levodopa, with chloranil was studied spectrophotometrically. The conditions were investigated and optimized. The interaction obeyed Beer＇s law over the range of 0.2-8.7, 1.2-20 and 2-26.4 μg/mL for aminobutyric acid, carbocisteine and levodopa, respectively. The validity was compared with that by the official methods^1,3,5 and the recovery studies of standard addition method, the result is satisfactory. The proposed method has been successfully applied to the determination of the above drugs in tablets.

关 键 词：Aminobutyric acid CARBOCISTEINE LEVODOPA CHLORANIL spectrophotometry. 

分 类 号：R977.4[医药卫生—药品] R917[医药卫生—药学]