伏格特-小柳原田病患者的多焦视网膜电图观察  

The changes of multifocal electroretinogram in the patients with Vogt-Koyanagi-Harada syndromey

作　　者：陈青山[1] 曾键[1] 赵铁英[1] 王琳丽[1] 辛欣[1] 古洵清[1] 

机构地区：[1]深圳市眼科医院暨南大学医学院深圳眼科中心,深圳518001

出　　处：《中国中医眼科杂志》2006年第3期133-135,共3页China Journal of Chinese Ophthalmology

摘　　要：目的探讨多焦视网膜电图对伏格特-小柳原田病(Vogt-Koyangi-Harada disease,VKH)患者皮质类固醇治疗前后视功能评价的意义。方法观察25例(50只眼)VKH患者在皮质类固醇治疗前后的MERG变化,对1环、1-3环、4-6环及1-6环的N波、P波的振幅密度和潜伏期进行对照。结果治疗后较治疗前的1环、1-3环、4-6环、1-6环N波、P波的振幅密度和潜伏期差异均有显著性(P<0.05)。结论mERG能够客观反映VKH患者黄斑中心凹和黄斑区视功能的损害程度,是评价VKH病变视功能变化的有效方法之一。OBJECTIVE To measure and compare the difference of multifocal electroretinogram （MERG） in the patients with Vogt - Koyanagi - Harada syndrome （VKH） treated with corticosteroid therapy. METHODS Twenty five patients （50 eyes） with VKH were examined by MERG before and after treatment.The N wave P wave latencies and amplitude densities of 1 ring, 1 - 3 rings, 4 - 6 rings and 1 - 6 rings before the treatment were compared with those after treatment. RESULTS The latencies of 1 ring, 1 - 3 rings, 4 - 6 rings and 1 - 6 rings in VKH were decreased after the treatment compared with before the treatment, the amplitude densities in VKH were higher after treatment than before the treatment, there were significant difference （ P 〈 0.05） . CONCLUSIONS MERG can be used to evaluate macular fovea and macular area damage in patients with VKH.

关 键 词：伏格特-小柳原田病 皮质类固醇 多焦视网膜电图 

分 类 号：R773.9[医药卫生—眼科]