外阴癌转移复发分析  

Analysis of Metastasis and Recurrence of Carcinoma of the Vulva

作　　者：周雷[1] 王耕辛[1] 张连郁[2] 

机构地区：[1]天津医科大学附属肿瘤医院盆腔科,天津市300060 [2]天津医科大学附属肿瘤医院病理科,天津市300060

出　　处：《中国肿瘤临床》2006年第15期888-890,共3页Chinese Journal of Clinical Oncology

摘　　要：目的:总结影响外阴癌预后、转移复发的相关因素,探讨理想的治疗方法。方法:分析本院1970年1月至2000年1月收治的162例外阴癌,比较不同治疗方法、分期以及不同复发时间、部位对5年生存率的影响。结果:162例患者总的5年生存率为60.5%,其中外阴鳞癌5年生存率为68.7%。复发率为34.3%,复发部位单纯外阴占40.0%,腹股沟淋巴结占42.2%,盆腔淋巴结转移占6.7%,远处转移11.1%。结论:外阴癌复发者外阴白斑发病比例高于未复发者(P<0.05),复发部位是影响预后的重要因素,2年内复发者预后差。外科手术是影响外阴局部复发的主要因素。Objective： To evaluate the optimal treatment and outcome of recurrent vulvar cancer. Methods： In a retrospective review of 162 cases with vulvar carcinoma between 1970 and 2000, there was an incidence rate of 2.9% of all female genital neoplasms. The different surgical strategies and various prognostic factors affecting recurrence were compared. Results： The overall 5-year survival of vulvar squamous cancer was 68.7% （90/131）. The recurrence rate was 34.3% （45/131）. Distribution of recurrence was as follows： 40.0% in the vulva, 42.2% in the inguinal region, 6.7% in the pelvic cavity and 11.1% as distant metastases. Conclusion： The rate of morbidity due to leukoplakia vulvae in the recurrent cases is higher than that of patients without recurrence （P〈0.05）. The physical location of the recurrence is an important factor affecting the prognosis. The prognosis is poor for those suffering recurrence within 2 years. Surgical intervention is the main treatment for decreasing the incidence of local recurrence of carcinoma of the vulva.

关 键 词：外阴肿瘤 转移复发 外科手术 预后 

分 类 号：R737.35[医药卫生—肿瘤]