雷诺氏综合征患者血液高凝状态的研究  

Hypercoagulative Status in Raynaud's Syndrome Patients

作　　者：蒋国成 陈唤青[2] 周佩文[2] 黄石兵[2] 

机构地区：[1]江苏通州市人民医院,226300 [2]南通医学院附属医院

出　　处：《天津医药》1996年第11期661-663,共3页Tianjin Medical Journal

摘　　要：报道20例RDS(SLE所致10例,病因不明10例),研究其PAGT”、VWF:Ag、Fn、APTT、ATⅢ:Ag、ATⅢ:C、PLG可能反映高凝指标的变化。结果原发性RDS与SLE引起的RDS组间无显著统计差异(均P>0.05),其中PAGT、VWF:Ag、Fn都显著增高(P<0.05)。表明RDS患者均存在血小板活性增强的高凝状态及血管内皮的损伤。少部分患者有凝血、抗凝血及纤溶的改变。Twenty cases of Raynaud's syndrome(RDS)were entered in the study 110 cases were primary, 10 cases caused by systemic lupus erythematosus). The following studies were done on all subjects:platelet aggregation rate (PAGT ) , VWF:Ag, APTT, fibronection (Fn ) , ATIII: Ag, ATIII : C and plasminogen (PLG). The levels of PAGT,Fn and VWF:Ag dominantly increased(P<0. 05). The results indicated that all RDS patients were of the hypercoagulative status due to the increase of platelet activity and the vascular endothelial damage. Some patients were due to the changes of coagulation , anti-coagulation and fibrinolysis mechanism.

关 键 词：Raynaud综合征 雷诺氏综合征 高凝状态 血液 

分 类 号：R747.302[医药卫生—神经病学与精神病学]