精神分裂症患者系统家庭治疗的疗效研究  

The control treat of systemic family treatment for schizophrenic patients

作　　者：张明廉[1] 袁国桢[1] 姚建军[1] 倪素琴[1] 张霞[1] 安宝富[1] 周德祥[1] 包召华[1] 

机构地区：[1]南京医科大学附属无锡市精神卫生中心精神科,无锡214151

出　　处：《中国行为医学科学》2006年第8期711-712,共2页Chinese Journal of Behavioral Medical Science

基　　金：无锡市科技发展项目(CS045010)

摘　　要：目的评估系统家庭治疗对精神分裂症患者的综合治疗效果和对照料者心身健康的影响。方法采用随机抽样的方法,将150例精神分裂症患者分为治疗组和对照组,在2组均使用抗精神病药物治疗的基础上,仅对治疗组辅以系统家庭治疗,治疗前后评估临床疗效及亲属的心身健康状况。结果在随访1年末,治疗组和对照组年复发率分别为19．0%和35．4%(P＜0．05),随访2年末分别为15．9%和33．8%(P＜0．05)。治疗组出院时和随访30个月末PANSS评分分别为(60．5±7．8)分和(46．8±8．1)分( P＜0．01),对照组分别为(57．5±8．6)分和(57．0±8．0)分(P＞0．05)。治疗组和对照组DAS评分入院时分别为(17．8±3．7)分和(16．8±8．1)分(P＞0．05),出院时分别为(8．1±2．7)分和(9．3±2．9)分(P＜0．05),随访30个月末分别为(6．7±4．9)分和(14．5±8．3)分(P＞0．01)。治疗组治疗前和随访30个月末GHQ评分分别为(4．8±4．1)分和(3．1±2．6)分(P＜0．01)。结论系统家庭治疗可以降低精神分裂症患者的复发率,减轻其精神症状和社会功能残疾程度,并在一定程度上改善照料者心身健康状况。Objective The aim of this study was to evaluate the curative effect of systemic family treatment for schizophrenic patients and the effect of mental and physical health for the relatives of patients. Methods 150 patients with schizophrenia and their family members were randomly divided into family group（ n = 75）and control group （ n = 75 ）. The cases in family group were provided systemic family treatment, while the control group were only followed by regular clinic visits. Results The relapse rates of psychotic symptoms in family and control groups were 19.0% and 35.4% at the end of 1st year,15.9% and 33.8% （P〈0.05） at the end of 2nd years respectively. The PANSS scores in family groups were （60.5 ± 7.8 ） and （46.8 ± 8.1 ） （ P 〈 0.01 ） at outhospital and the end of 30th month respectively. The PANSS scores of control group were（57.5 ± 8.6） and （ 57.0 ± 8.0） at outhospital and the 30th month respectively. The DAS scores of family group and control group were （ 17.8 ± 3.7） and （16.8±8.1） at baseline and （8.1 ±2.7） and （9.3±2.9） at outhospital and （6.7±4.9） and （14. 5 ± 8.3） at the end of 30th month respectively. The GHQ scores of family groups were （4.8 ± 4.1 ） and （3.1 ± 2.6） （ P 〈 0.01 ） at baseline and the end of 30th month respectively. The GHQ scores of control group were （4. 5 ± 3.9） and （4.7 ± 3.8） at baseline and the end of 30th month respectively. Conclusion Systemic family treatment can reduces the relapse of schizophrenia ,improve the symptoms and the social function, also improve mental and physical health of the relatives of patients.

关 键 词：精神分裂症 系统家庭治疗 疗效 随访研究 

分 类 号：R749.3[医药卫生—神经病学与精神病学] R749.055[医药卫生—临床医学]